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Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington's disease.
Bertoglio D, Verhaeghe J, Miranda A, Wyffels L, Stroobants S, Mrzljak L, Khetarpal V, Skinbjerg M, Liu L, Dominguez C, Munoz-Sanjuan I, Bard J, Staelens S. Bertoglio D, et al. Among authors: staelens s. Eur J Nucl Med Mol Imaging. 2022 Mar;49(4):1166-1175. doi: 10.1007/s00259-021-05578-8. Epub 2021 Oct 15. Eur J Nucl Med Mol Imaging. 2022. PMID: 34651228 Free PMC article.
Preclinical evaluation of the novel [18F]CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease.
Zajicek F, Verhaeghe J, De Lombaerde S, Van Eetveldt A, Miranda A, Munoz-Sanjuan I, Dominguez C, Khetarpal V, Bard J, Liu L, Staelens S, Bertoglio D. Zajicek F, et al. Among authors: staelens s. Eur J Nucl Med Mol Imaging. 2024 Dec;52(1):122-133. doi: 10.1007/s00259-024-06880-x. Epub 2024 Aug 27. Eur J Nucl Med Mol Imaging. 2024. PMID: 39190197 Free PMC article.
Validation and noninvasive kinetic modeling of [11C]UCB-J PET imaging in mice.
Bertoglio D, Verhaeghe J, Miranda A, Kertesz I, Cybulska K, Korat Š, Wyffels L, Stroobants S, Mrzljak L, Dominguez C, Liu L, Skinbjerg M, Munoz-Sanjuan I, Staelens S. Bertoglio D, et al. Among authors: staelens s. J Cereb Blood Flow Metab. 2020 Jun;40(6):1351-1362. doi: 10.1177/0271678X19864081. Epub 2019 Jul 15. J Cereb Blood Flow Metab. 2020. PMID: 31307287 Free PMC article.
181 results