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Integrative analysis of patient-derived tumoroids and ex vivo organoid modeling of ARID1A loss in bladder cancer reveals therapeutic molecular targets.
Scholtes MP, Akbarzadeh M, Galaras A, Nakauma-Gonzáles JA, Bazrafshan A, Solanki V, Torenvliet B, Beikmohammadi L, Lozovanu V, Romal S, Moulos P, Vavouraki N, Kan TW, Algoe M, van Royen ME, Sacchetti A, van den Bosch TPP, Eussen B, de Klein A, van Leenders GJLH, Boormans JL, Hatzis P, Palstra RJ, Zuiverloon TCM, Mahmoudi T. Scholtes MP, et al. Among authors: van den bosch tpp. Cancer Lett. 2025 Jan 29:217506. doi: 10.1016/j.canlet.2025.217506. Online ahead of print. Cancer Lett. 2025. PMID: 39892702 Free article.
A Repurposed Drug Selection Pipeline to Identify CNS-Penetrant Drug Candidates for Glioblastoma.
Ntafoulis I, Koolen SLW, van Tellingen O, den Hollander CWJ, Sabel-Goedknegt H, Dijkhuizen S, Haeck J, Reuvers TGA, de Bruijn P, van den Bosch TPP, van Dis V, Gao Z, Dirven CMF, Leenstra S, Lamfers MLM. Ntafoulis I, et al. Among authors: van den bosch tpp. Pharmaceuticals (Basel). 2024 Dec 14;17(12):1687. doi: 10.3390/ph17121687. Pharmaceuticals (Basel). 2024. PMID: 39770529 Free PMC article.
Human Enteric Glia Diversity in Health and Disease: New Avenues for the Treatment of Hirschsprung Disease.
Windster JD, Kakiailatu NJM, Kuil LE, Antanaviciute A, Sacchetti A, MacKenzie KC, Peulen-Zink J, Kan TW, Bindels E, de Pater E, Doukas M, van den Bosch TPP, Yousefi S, Barakat TS, Meeussen CJHM, Sloots PCEJ, Wijnen RMH, Parikh K, Boesmans W, Melotte V, Hofstra RMW, Simmons A, Alves MM. Windster JD, et al. Among authors: van den bosch tpp. Gastroenterology. 2024 Dec 24:S0016-5085(24)05803-7. doi: 10.1053/j.gastro.2024.12.011. Online ahead of print. Gastroenterology. 2024. PMID: 39725172 Free article.
Identification of Defined Molecular Subgroups on the Basis of Immunohistochemical Analyses and Potential Therapeutic Vulnerabilities of Pulmonary Carcinoids.
Leunissen DJG, Moonen L, von der Thüsen JH, den Bakker MA, Hillen LM, van Weert TJJ, Zur Hausen A, van den Bosch TPP, Lap LMV, Damhuis RA, Reynaert NL, van den Broek EC; PALGA group; Fernandez-Cuesta L, Foll M, Alcala N, Sexton-Oates A, Dingemans AC, Speel EM, Derks JL. Leunissen DJG, et al. Among authors: van den bosch tpp. J Thorac Oncol. 2024 Nov 22:S1556-0864(24)02481-X. doi: 10.1016/j.jtho.2024.11.018. Online ahead of print. J Thorac Oncol. 2024. PMID: 39581377 Free article.
The Impact of Spliceosome Inhibition in SF3B1-Mutated Uveal Melanoma.
Nguyen JQN, Drabarek W, Leeflang AMCHJ, Brands T, van den Bosch TPP, Verdijk RM, van de Werken HJG, van Riet J, Paridaens D, de Klein A, Brosens E, Kiliç E; Rotterdam Ocular Melanoma Study Group. Nguyen JQN, et al. Among authors: van den bosch tpp. Invest Ophthalmol Vis Sci. 2024 Oct 1;65(12):11. doi: 10.1167/iovs.65.12.11. Invest Ophthalmol Vis Sci. 2024. PMID: 39374010 Free PMC article.
Development of an Ex Vivo Functional Assay for Prediction of Irradiation Related Toxicity in Healthy Oral Mucosa Tissue.
Pachler KS, Lauwers I, Verkaik NS, Rovituso M, van der Wal E, Mast H, Jonker BP, Sewnaik A, Hardillo JA, Keereweer S, Monserez D, Kremer B, Koppes S, van den Bosch TPP, Verduijn GM, Petit S, Sørensen BS, van Gent DC, Capala ME. Pachler KS, et al. Among authors: van den bosch tpp. Int J Mol Sci. 2024 Jun 28;25(13):7157. doi: 10.3390/ijms25137157. Int J Mol Sci. 2024. PMID: 39000262 Free PMC article.
86 results