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Immune evasion in HPV- head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss.
William WN Jr, Zhao X, Bianchi JJ, Lin HY, Cheng P, Lee JJ, Carter H, Alexandrov LB, Abraham JP, Spetzler DB, Dubinett SM, Cleveland DW, Cavenee W, Davoli T, Lippman SM. William WN Jr, et al. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2022655118. doi: 10.1073/pnas.2022655118. Proc Natl Acad Sci U S A. 2021. PMID: 33952700 Free PMC article.
Somatic 9p24.1 alterations in HPV- head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity.
Zhao X, Cohen EEW, William WN Jr, Bianchi JJ, Abraham JP, Magee D, Spetzler DB, Gutkind JS, Alexandrov LB, Cavenee WK, Lippman SM, Davoli T. Zhao X, et al. Among authors: william wn jr. Proc Natl Acad Sci U S A. 2022 Nov 22;119(47):e2213835119. doi: 10.1073/pnas.2213835119. Epub 2022 Nov 17. Proc Natl Acad Sci U S A. 2022. PMID: 36395141 Free PMC article.
Spatial PD-L1, immune-cell microenvironment, and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort.
William WN Jr, Zhang J, Zhao X, Parra ER, Uraoka N, Lin HY, Peng SA, El-Naggar AK, Rodriguez-Canales J, Song J, Gillenwater AM, Wistuba II, Myers JN, Gold KA, Ferrarotto R, Hwu P, Davoli T, Lee JJ, Heymach JV, Papadimitrakopoulou VA, Lippman SM. William WN Jr, et al. Cancer. 2023 Mar 1;129(5):714-727. doi: 10.1002/cncr.34607. Epub 2023 Jan 3. Cancer. 2023. PMID: 36597662 Free PMC article.
Molecular targets for cancer chemoprevention.
William WN Jr, Heymach JV, Kim ES, Lippman SM. William WN Jr, et al. Nat Rev Drug Discov. 2009 Mar;8(3):213-25. doi: 10.1038/nrd2663. Nat Rev Drug Discov. 2009. PMID: 19247304 Review.
Randomized trial of 13-cis retinoic acid compared with retinyl palmitate with or without beta-carotene in oral premalignancy.
Papadimitrakopoulou VA, Lee JJ, William WN Jr, Martin JW, Thomas M, Kim ES, Khuri FR, Shin DM, Feng L, Hong WK, Lippman SM. Papadimitrakopoulou VA, et al. Among authors: william wn jr. J Clin Oncol. 2009 Feb 1;27(4):599-604. doi: 10.1200/JCO.2008.17.1850. Epub 2008 Dec 15. J Clin Oncol. 2009. PMID: 19075276 Free PMC article. Clinical Trial.
136 results