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Correction to "Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility".
Romero A, Ashcraft L, Chandra A, DiMassa V, Cremin P, Collibee SE, Chuang C, Hartman J, Hwee DT, St Jean D, Malinowski J, DeBenedetto M, Moebius DC, Payette J, Vargas R, Yeoman J, Motani A, Reagan J, Malik FI, Morgan BP. Romero A, et al. Among authors: chuang c. J Med Chem. 2025 Jan 9;68(1):850. doi: 10.1021/acs.jmedchem.4c02850. Epub 2024 Dec 26. J Med Chem. 2025. PMID: 39722587 Free PMC article. No abstract available.
Quinazolinone derivatives as orally available ghrelin receptor antagonists for the treatment of diabetes and obesity.
Rudolph J, Esler WP, O'connor S, Coish PD, Wickens PL, Brands M, Bierer DE, Bloomquist BT, Bondar G, Chen L, Chuang CY, Claus TH, Fathi Z, Fu W, Khire UR, Kristie JA, Liu XG, Lowe DB, McClure AC, Michels M, Ortiz AA, Ramsden PD, Schoenleber RW, Shelekhin TE, Vakalopoulos A, Tang W, Wang L, Yi L, Gardell SJ, Livingston JN, Sweet LJ, Bullock WH. Rudolph J, et al. Among authors: chuang cy. J Med Chem. 2007 Oct 18;50(21):5202-16. doi: 10.1021/jm070071+. Epub 2007 Sep 21. J Med Chem. 2007. PMID: 17887659
Indanylacetic acids as PPAR-delta activator insulin sensitizers.
Wickens P, Zhang C, Ma X, Zhao Q, Amatruda J, Bullock W, Burns M, Cantin LD, Chuang CY, Claus T, Dai M, Dela Cruz F, Dickson D, Ehrgott FJ, Fan D, Heald S, Hentemann M, Iwuagwu CI, Johnson JS, Kumarasinghe E, Ladner D, Lavoie R, Liang S, Livingston JN, Lowe D, Magnuson S, Mannelly G, Mugge I, Ogutu H, Pleasic-Williams S, Schoenleber RW, Shapiro J, Shelekhin T, Sweet L, Town C, Tsutsumi M. Wickens P, et al. Among authors: chuang cy. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4369-73. doi: 10.1016/j.bmcl.2007.03.057. Epub 2007 Mar 23. Bioorg Med Chem Lett. 2007. PMID: 17601734
SAR of a novel 'Anthranilamide Like' series of VEGFR-2, multi protein kinase inhibitors for the treatment of cancer.
Wickens P, Kluender H, Dixon J, Brennan C, Achebe F, Bacchiocchi A, Bankston D, Bierer D, Brands M, Braun D, Brown MS, Chuang CY, Dumas J, Enyedy I, Hofilena G, Hong Z, Housley T, Jones B, Khire U, Kreiman C, Kumarasinghe E, Lowinger T, Ott-Morgan R, Perkins L, Phillips B, Schoenleber R, Scott WJ, Sheeler R, Redman A, Sun X, Taylor I, Wang L, Wilhelm S, Zhang X, Zhang M, Sullivan E, Carter C, Miglarese M, Levy J. Wickens P, et al. Among authors: chuang cy. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4378-81. doi: 10.1016/j.bmcl.2007.02.075. Epub 2007 Mar 3. Bioorg Med Chem Lett. 2007. PMID: 17574417
Ethnic and racial differences in children and young people with respiratory and neurological post-acute sequelae of SARS-CoV-2: an electronic health record-based cohort study from the RECOVER Initiative.
Rao S, Azuero-Dajud R, Lorman V, Landeo-Gutierrez J, Rhee KE, Ryu J, Kim C, Carmilani M, Gross RS, Mohandas S, Suresh S, Bailey LC, Castro V, Senathirajah Y, Esquenazi-Karonika S, Murphy S, Caddle S, Kleinman LC, Castro-Baucom L, Oliveira CR, Klein JD, Chung A, Cowell LG, Madlock-Brown C, Geary CR, Sills MR, Thorpe LE, Szmuszkovicz J, Tantisira KG; RECOVER EHR and; RECOVER Pediatric Cohorts. Rao S, et al. EClinicalMedicine. 2025 Jan 2;80:103042. doi: 10.1016/j.eclinm.2024.103042. eCollection 2025 Feb. EClinicalMedicine. 2025. PMID: 39850015 Free PMC article.
PD-1 cis-targeted IL-2v in combination with radiotherapy inhibits lung cancer growth and remodels the immune microenvironment.
Godfroid C, Romero J, Labiano S, Chuang CH, Kelemen A, Wyss T, Roh V, Verdeil G, Klein C, Codarri Deak L, Umaña P, Tolstonog GV, Trumpfheller C, Vozenin MC, Romero PJ. Godfroid C, et al. Among authors: chuang ch. J Immunother Cancer. 2025 Jan 22;13(1):e009832. doi: 10.1136/jitc-2024-009832. J Immunother Cancer. 2025. PMID: 39848686 Free PMC article.
Clinical Trial: Precise Administration of Sucralfate Powder in Prevention of Delayed Postpolypectomy Bleeding. A Randomized Controlled Trial.
Chiang HC, Chen PJ, Yang EH, Kuo TL, Hsieh MT, Kang JW, Cheng HC, Chang WL, Chen WY, Chiu HC, Lin MY, Hong TC, Chiang CM, Chen WC, Huang KK, Lu MH, Wu MH, Chen CY, Lin XZ, Chuang CH. Chiang HC, et al. Among authors: chuang ch. Clin Transl Gastroenterol. 2025 Jan 21. doi: 10.14309/ctg.0000000000000818. Online ahead of print. Clin Transl Gastroenterol. 2025. PMID: 39836033
2,928 results