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Disruption of deoxyribonucleotide triphosphate biosynthesis leads to RAS proto-oncogene activation and perturbation of mitochondrial metabolism.
Suspène R, Raymond KA, Guardado-Calvo P, Dairou J, Bonhomme F, Bonenfant C, Guyetant S, Lecomte T, Pagès JC, Vartanian JP. Suspène R, et al. Among authors: vartanian jp. J Biol Chem. 2024 Dec 23;301(2):108117. doi: 10.1016/j.jbc.2024.108117. Online ahead of print. J Biol Chem. 2024. PMID: 39722416 Free article.
Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A.
Aynaud MM, Suspène R, Vidalain PO, Mussil B, Guétard D, Tangy F, Wain-Hobson S, Vartanian JP. Aynaud MM, et al. Among authors: vartanian jp. J Biol Chem. 2012 Nov 9;287(46):39182-92. doi: 10.1074/jbc.M112.372722. Epub 2012 Sep 13. J Biol Chem. 2012. PMID: 22977230 Free PMC article.
Antagonism of ALAS1 by the Measles Virus V protein contributes to degradation of the mitochondrial network and promotes interferon response.
Khalfi P, Suspène R, Raymond KA, Caval V, Caignard G, Berry N, Thiers V, Combredet C, Rufie C, Rigaud S, Ghozlane A, Volant S, Komarova AV, Tangy F, Vartanian JP. Khalfi P, et al. Among authors: vartanian jp. PLoS Pathog. 2023 Feb 21;19(2):e1011170. doi: 10.1371/journal.ppat.1011170. eCollection 2023 Feb. PLoS Pathog. 2023. PMID: 36802406 Free PMC article.
The APOBEC3B cytidine deaminase is an adenovirus restriction factor.
Lejeune N, Mathieu S, Decloux A, Poulain F, Blockx Z, Raymond KA, Willemart K, Vartanian JP, Suspène R, Gillet NA. Lejeune N, et al. Among authors: vartanian jp. PLoS Pathog. 2023 Feb 6;19(2):e1011156. doi: 10.1371/journal.ppat.1011156. eCollection 2023 Feb. PLoS Pathog. 2023. PMID: 36745676 Free PMC article.
84 results