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Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses.
Reid KT, Colpitts SJ, Mathews JA, Santos Carreira A, Murphy JM, Borovsky DT, Jegatheeswaran S, Cui W, Alfaro Moya T, Sachewsky N, An J, Xia Y, Mortha A, Lee JB, Zhang L, Novitzky-Basso I, Mattsson J, Crome SQ. Reid KT, et al. Among authors: crome sq. Cell Rep. 2024 Dec 24;44(1):115102. doi: 10.1016/j.celrep.2024.115102. Online ahead of print. Cell Rep. 2024. PMID: 39721022 Free article.
Single cell profiling of hematopoietic stem cell transplant recipients reveals TGF-β1 and IL-2 confer immunoregulatory functions to NK cells.
Mathews JA, Borovsky DT, Reid KT, Murphy JM, Colpitts SJ, Carreira AS, Moya TA, Chung DC, Novitzky-Basso I, Mattsson J, Ohashi PS, Crome SQ. Mathews JA, et al. Among authors: crome sq. iScience. 2024 Nov 18;27(12):111416. doi: 10.1016/j.isci.2024.111416. eCollection 2024 Dec 20. iScience. 2024. PMID: 39720529 Free PMC article.
Generation of an Inhibitory NK Cell Subset by TGF-β1/IL-15 Polarization.
Chung DC, Garcia-Batres CR, Millar DG, Wong SWY, Elford AR, Mathews JA, Wang BX, Nguyen LT, Shaw PA, Clarke BA, Bernardini MQ, Sacher AG, Crome SQ, Ohashi PS. Chung DC, et al. Among authors: crome sq. J Immunol. 2024 Jun 15;212(12):1904-1912. doi: 10.4049/jimmunol.2300834. J Immunol. 2024. PMID: 38668728 Free PMC article.
Strategies for optimizing CITE-seq for human islets and other tissues.
Colpitts SJ, Budd MA, Monajemi M, Reid KT, Murphy JM, Ivison S, Verchere CB, Levings MK, Crome SQ. Colpitts SJ, et al. Among authors: crome sq. Front Immunol. 2023 Mar 1;14:1107582. doi: 10.3389/fimmu.2023.1107582. eCollection 2023. Front Immunol. 2023. PMID: 36936943 Free PMC article.
Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity.
McEvoy CM, Murphy JM, Zhang L, Clotet-Freixas S, Mathews JA, An J, Karimzadeh M, Pouyabahar D, Su S, Zaslaver O, Röst H, Arambewela R, Liu LY, Zhang S, Lawson KA, Finelli A, Wang B, MacParland SA, Bader GD, Konvalinka A, Crome SQ. McEvoy CM, et al. Among authors: crome sq. Nat Commun. 2022 Dec 10;13(1):7634. doi: 10.1038/s41467-022-35297-z. Nat Commun. 2022. PMID: 36496458 Free PMC article.
Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses.
Currie EG, Coburn B, Porfilio EA, Lam P, Rojas OL, Novak J, Yang S, Chowdhury RB, Ward LA, Wang PW, Khaleghi K, An J, Crome SQ, Hladunewich MA, Barbour SJ, Cattran DC, Parekh RS, Licht C, John R, Kaul R, Croitoru K, Gray-Owen SD, Guttman DS, Gommerman JL, Reich HN. Currie EG, et al. Among authors: crome sq. JCI Insight. 2022 Mar 8;7(5):e141289. doi: 10.1172/jci.insight.141289. JCI Insight. 2022. PMID: 35133979 Free PMC article.
31 results