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Page 1
Hyperaminoacidemia from interrupted glucagon signaling increases pancreatic acinar cell proliferation and size via mTORC1 and YAP pathways.
Dai C, Zhang Y, Gong Y, Bradley A, Tang Z, Sellick K, Shrestha S, Spears E, Covington BA, Stanley J, Jenkins R, Richardson TM, Brantley RA, Coate K, Saunders DC, Wright JJ, Brissova M, Dean ED, Powers AC, Chen W. Dai C, et al. Among authors: coate k. iScience. 2024 Nov 22;27(12):111447. doi: 10.1016/j.isci.2024.111447. eCollection 2024 Dec 20. iScience. 2024. PMID: 39720531 Free PMC article.
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2.
Spears E, Stanley JE, Shou M, Yin L, Li X, Dai C, Bradley A, Sellick K, Poffenberger G, Coate KC, Shrestha S, Jenkins R, Sloop KW, Wilson KT, Attie AD, Keller MP, Chen W, Powers AC, Dean ED. Spears E, et al. Among authors: coate kc. bioRxiv [Preprint]. 2023 Aug 14:2023.08.10.552656. doi: 10.1101/2023.08.10.552656. bioRxiv. 2023. PMID: 37645716 Free PMC article. Preprint.
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Spears E, Poffenberger G, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. bioRxiv [Preprint]. 2024 Aug 7:2024.08.06.606926. doi: 10.1101/2024.08.06.606926. bioRxiv. 2024. Update in: Mol Metab. 2024 Dec;90:102050. doi: 10.1016/j.molmet.2024.102050 PMID: 39149351 Free PMC article. Updated. Preprint.
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Sellick K, Spears E, Poffenberger G, Schornack AMR, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. Mol Metab. 2024 Dec;90:102050. doi: 10.1016/j.molmet.2024.102050. Epub 2024 Oct 20. Mol Metab. 2024. PMID: 39433176 Free PMC article.
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells.
Coate KC, Cha J, Shrestha S, Wang W, Gonçalves LM, Almaça J, Kapp ME, Fasolino M, Morgan A, Dai C, Saunders DC, Bottino R, Aramandla R, Jenkins R, Stein R, Kaestner KH, Vahedi G; HPAP Consortium; Brissova M, Powers AC. Coate KC, et al. Cell Metab. 2020 Dec 1;32(6):1028-1040.e4. doi: 10.1016/j.cmet.2020.11.006. Epub 2020 Nov 13. Cell Metab. 2020. PMID: 33207245 Free PMC article.
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells.
Coate KC, Cha J, Shrestha S, Wang W, Gonçalves LM, Almaça J, Kapp ME, Fasolino M, Morgan A, Dai C, Saunders DC, Bottino R, Aramandla R, Jenkins R, Stein R, Kaestner KH, Vahedi G, Consortium H, Brissova M, Powers AC. Coate KC, et al. bioRxiv [Preprint]. 2020 Oct 20:2020.08.31.275719. doi: 10.1101/2020.08.31.275719. bioRxiv. 2020. Update in: Cell Metab. 2020 Dec 1;32(6):1028-1040.e4. doi: 10.1016/j.cmet.2020.11.006 PMID: 33106804 Free PMC article. Updated. Preprint.
Glucagon's effect on liver protein metabolism in vivo.
Kraft G, Coate KC, Winnick JJ, Dardevet D, Donahue EP, Cherrington AD, Williams PE, Moore MC. Kraft G, et al. Am J Physiol Endocrinol Metab. 2017 Sep 1;313(3):E263-E272. doi: 10.1152/ajpendo.00045.2017. Epub 2017 May 23. Am J Physiol Endocrinol Metab. 2017. PMID: 28536182 Free PMC article.
39 results