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Stochastic neuropeptide signals compete to calibrate the rate of satiation.
Zhang SX, Kim A, Madara JC, Zhu PK, Christenson LF, Lutas A, Kalugin PN, Sunkavalli PS, Jin Y, Pal A, Tian L, Lowell BB, Andermann ML. Zhang SX, et al. Among authors: madara jc. Nature. 2025 Jan;637(8044):137-144. doi: 10.1038/s41586-024-08164-8. Epub 2024 Nov 6. Nature. 2025. PMID: 39506113
Competition between stochastic neuropeptide signals calibrates the rate of satiation.
Zhang SX, Kim A, Madara JC, Zhu PK, Christenson LF, Lutas A, Kalugin PN, Jin Y, Pal A, Tian L, Lowell BB, Andermann ML. Zhang SX, et al. Among authors: madara jc. Res Sq [Preprint]. 2023 Jul 26:rs.3.rs-3185572. doi: 10.21203/rs.3.rs-3185572/v1. Res Sq. 2023. Update in: Nature. 2024 Nov 6. doi: 10.1038/s41586-024-08164-8 PMID: 37546985 Free PMC article. Updated. Preprint.
Competition between stochastic neuropeptide signals calibrates the rate of satiation.
Zhang SX, Kim A, Madara JC, Zhu PK, Christenson LF, Lutas A, Kalugin PN, Jin Y, Pal A, Tian L, Lowell BB, Andermann ML. Zhang SX, et al. Among authors: madara jc. bioRxiv [Preprint]. 2023 Jul 12:2023.07.11.548551. doi: 10.1101/2023.07.11.548551. bioRxiv. 2023. Update in: Nature. 2024 Nov 6. doi: 10.1038/s41586-024-08164-8 PMID: 37503012 Free PMC article. Updated. Preprint.
A synaptic amplifier of hunger for regaining body weight in the hypothalamus.
Grzelka K, Wilhelms H, Dodt S, Dreisow ML, Madara JC, Walker SJ, Wu C, Wang D, Lowell BB, Fenselau H. Grzelka K, et al. Among authors: madara jc. Cell Metab. 2023 May 2;35(5):770-785.e5. doi: 10.1016/j.cmet.2023.03.002. Epub 2023 Mar 24. Cell Metab. 2023. PMID: 36965483 Free PMC article.
Transient cAMP production drives rapid and sustained spiking in brainstem parabrachial neurons to suppress feeding.
Alvarado JS, Lutas A, Madara JC, Isaac J, Lommer C, Andermann ML. Alvarado JS, et al. Among authors: madara jc. bioRxiv [Preprint]. 2023 Mar 1:2023.02.25.530033. doi: 10.1101/2023.02.25.530033. bioRxiv. 2023. Update in: Neuron. 2024 May 1;112(9):1416-1425.e5. doi: 10.1016/j.neuron.2024.02.002 PMID: 36865343 Free PMC article. Updated. Preprint.
Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes.
Kim A, Knudsen JG, Madara JC, Benrick A, Hill TG, Abdul Kadir L, Kellard JA, Mellander L, Miranda C, Lin H, James T, Suba K, Spigelman AF, Wu Y, MacDonald PE, Wernstedt Asterholm I, Magnussen T, Christensen M, Vilsbøll T, Salem V, Knop FK, Rorsman P, Lowell BB, Briant LJ. Kim A, et al. Among authors: madara jc. Elife. 2021 Nov 17;10:e72919. doi: 10.7554/eLife.72919. Elife. 2021. PMID: 34787082 Free PMC article.
32 results