Leys D - Search Results

1

SignatureFinder enables sequence mining to identify cobalamin-dependent photoreceptor proteins.

Yu Y, Jeffreys LN, Poddar H, Hill A, Johannissen L, Dai F, Sakuma M, Leys D, Heyes DJ, Zhang S, Scrutton NS. Yu Y, et al. Among authors: leys d. FEBS J. 2024 Dec 24. doi: 10.1111/febs.17377. Online ahead of print. FEBS J. 2024. PMID: 39718193

2

A guide to time-resolved structural analysis of light-activated proteins.

Poddar H, Heyes DJ, Schirò G, Weik M, Leys D, Scrutton NS. Poddar H, et al. Among authors: leys d. FEBS J. 2022 Feb;289(3):576-595. doi: 10.1111/febs.15880. Epub 2021 May 1. FEBS J. 2022. PMID: 33864718 Free article. Review.

3

Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis. Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans.

Hothi P, Khadra KA, Combe JP, Leys D, Scrutton NS. Hothi P, et al. Among authors: leys d. FEBS J. 2005 Nov;272(22):5894-909. doi: 10.1111/j.1742-4658.2005.04990.x. FEBS J. 2005. PMID: 16279953 Free article.

4

Crystal structure and solution characterization of the activation domain of human methionine synthase.

Wolthers KR, Toogood HS, Jowitt TA, Marshall KR, Leys D, Scrutton NS. Wolthers KR, et al. Among authors: leys d. FEBS J. 2007 Feb;274(3):738-50. doi: 10.1111/j.1742-4658.2006.05618.x. FEBS J. 2007. PMID: 17288554 Free article.

5

Mechanistic aspects and redox properties of hyperthermophilic L-proline dehydrogenase from Pyrococcus furiosus related to dimethylglycine dehydrogenase/oxidase.

Monaghan PJ, Leys D, Scrutton NS. Monaghan PJ, et al. Among authors: leys d. FEBS J. 2007 Apr;274(8):2070-87. doi: 10.1111/j.1742-4658.2007.05750.x. Epub 2007 Mar 20. FEBS J. 2007. PMID: 17371548 Free article.

6

Dynamics driving function: new insights from electron transferring flavoproteins and partner complexes.

Toogood HS, Leys D, Scrutton NS. Toogood HS, et al. Among authors: leys d. FEBS J. 2007 Nov;274(21):5481-504. doi: 10.1111/j.1742-4658.2007.06107.x. Epub 2007 Oct 17. FEBS J. 2007. PMID: 17941859 Free article. Review.

7

Glutamate 338 is an electrostatic facilitator of C-Co bond breakage in a dynamic/electrostatic model of catalysis by ornithine aminomutase.

Menon BR, Menon N, Fisher K, Rigby SE, Leys D, Scrutton NS. Menon BR, et al. Among authors: leys d. FEBS J. 2015 Apr;282(7):1242-55. doi: 10.1111/febs.13215. Epub 2015 Feb 12. FEBS J. 2015. PMID: 25627283 Free PMC article.

8

A common mechanism for coenzyme cobalamin-dependent reductive dehalogenases.

Johannissen LO, Leys D, Hay S. Johannissen LO, et al. Among authors: leys d. Phys Chem Chem Phys. 2017 Feb 22;19(8):6090-6094. doi: 10.1039/c6cp08659d. Phys Chem Chem Phys. 2017. PMID: 28191552

9

Structure of the Cannabis sativa olivetol-producing enzyme reveals cyclization plasticity in type III polyketide synthases.

Kearsey LJ, Prandi N, Karuppiah V, Yan C, Leys D, Toogood H, Takano E, Scrutton NS. Kearsey LJ, et al. Among authors: leys d. FEBS J. 2020 Apr;287(8):1511-1524. doi: 10.1111/febs.15089. Epub 2019 Oct 28. FEBS J. 2020. PMID: 31605668 Free PMC article.

10

Redox driven B₁₂-ligand switch drives CarH photoresponse.

Poddar H, Rios-Santacruz R, Heyes DJ, Shanmugam M, Brookfield A, Johannissen LO, Levy CW, Jeffreys LN, Zhang S, Sakuma M, Colletier JP, Hay S, Schirò G, Weik M, Scrutton NS, Leys D. Poddar H, et al. Among authors: leys d. Nat Commun. 2023 Aug 21;14(1):5082. doi: 10.1038/s41467-023-40817-6. Nat Commun. 2023. PMID: 37604813 Free PMC article.

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