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Page 1
Probing Ferryl Reactivity in a Nonheme Iron Oxygenase Using an Expanded Genetic Code.
Hardy FJ, Quesne MG, Gérard EF, Zhao J, Ortmayer M, Taylor CJ, Ali HS, Slater JW, Levy CW, Heyes DJ, Bollinger JM Jr, de Visser SP, Green AP. Hardy FJ, et al. Among authors: heyes dj. ACS Catal. 2024 Jul 20;14(15):11584-11590. doi: 10.1021/acscatal.4c02365. eCollection 2024 Aug 2. ACS Catal. 2024. PMID: 39114090 Free PMC article.
Photocobilins integrate B12 and bilin photochemistry for enzyme control.
Zhang S, Jeffreys LN, Poddar H, Yu Y, Liu C, Patel K, Johannissen LO, Zhu L, Cliff MJ, Yan C, Schirò G, Weik M, Sakuma M, Levy CW, Leys D, Heyes DJ, Scrutton NS. Zhang S, et al. Among authors: heyes dj. Nat Commun. 2024 Mar 28;15(1):2740. doi: 10.1038/s41467-024-46995-1. Nat Commun. 2024. PMID: 38548733 Free PMC article.
Mapping the Initial Stages of a Protective Pathway that Enhances Catalytic Turnover by a Lytic Polysaccharide Monooxygenase.
Zhao J, Zhuo Y, Diaz DE, Shanmugam M, Telfer AJ, Lindley PJ, Kracher D, Hayashi T, Seibt LS, Hardy FJ, Manners O, Hedison TM, Hollywood KA, Spiess R, Cain KM, Diaz-Moreno S, Scrutton NS, Tovborg M, Walton PH, Heyes DJ, Green AP. Zhao J, et al. Among authors: heyes dj. J Am Chem Soc. 2023 Sep 20;145(37):20672-20682. doi: 10.1021/jacs.3c06607. Epub 2023 Sep 9. J Am Chem Soc. 2023. PMID: 37688545 Free PMC article.
Redox driven B12-ligand switch drives CarH photoresponse.
Poddar H, Rios-Santacruz R, Heyes DJ, Shanmugam M, Brookfield A, Johannissen LO, Levy CW, Jeffreys LN, Zhang S, Sakuma M, Colletier JP, Hay S, Schirò G, Weik M, Scrutton NS, Leys D. Poddar H, et al. Among authors: heyes dj. Nat Commun. 2023 Aug 21;14(1):5082. doi: 10.1038/s41467-023-40817-6. Nat Commun. 2023. PMID: 37604813 Free PMC article.
Catalysis by Nature's photoenzymes.
Taylor A, Heyes DJ, Scrutton NS. Taylor A, et al. Among authors: heyes dj. Curr Opin Struct Biol. 2022 Dec;77:102491. doi: 10.1016/j.sbi.2022.102491. Epub 2022 Oct 30. Curr Opin Struct Biol. 2022. PMID: 36323132 Free article. Review.
102 results