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A Phase 1 randomized trial of homologous and heterologous filovirus vaccines with a late booster dose.
Rostad CA, Yildirim I, Kao C, Yi J, Kamidani S, Peters E, Stephens K, Gibson T, Hsiao HM, Singh K, Spearman P, McCracken C, Agbakoba V, Tomashek KM, Goll JB, Gelber CE, Johnson RA, Lee S, Maner-Smith K, Bosinger S, Ortlund EA, Chen X, Anderson LJ, Wrammert J, Suthar M, Rouphael N, Anderson EJ. Rostad CA, et al. Among authors: spearman p. NPJ Vaccines. 2024 Dec 23;9(1):255. doi: 10.1038/s41541-024-01042-4. NPJ Vaccines. 2024. PMID: 39715748 Free PMC article.
Anti-neuraminidase and anti-hemagglutinin stalk responses to different influenza a(H7N9) vaccine regimens.
El Sahly HM, Anderson EJ, Jackson LA, Neuzil KM, Atmar RL, Bernstein DI, Chen WH, Creech CB, Frey SE, Goepfert P, Meier J, Phadke V, Rouphael N, Rupp R, Stapleton JT, Spearman P, Walter EB, Winokur PL, Yildirim I, Williams TL, Oshinsky J, Coughlan L, Nijhuis H, Pasetti MF, Krammer F, Stadlbauer D, Nachbagauer R, Tsong R, Wegel A, Roberts PC. El Sahly HM, et al. Among authors: spearman p. Vaccine. 2025 Jan 4;47:126689. doi: 10.1016/j.vaccine.2024.126689. Online ahead of print. Vaccine. 2025. PMID: 39756216
Polytopic fractional delivery of an HIV vaccine alters cellular responses and results in increased epitope breadth in a phase 1 randomized trial.
Miner MD, deCamp A, Grunenberg N, De Rosa SC, Fiore-Gartland A, Bar K, Spearman P, Allen M, Yu PC, Manso B, Frahm N, Kalams S, Baden L, Keefer MC, Scott HM, Novak R, Van Tieu H, Tomaras GD, Kublin JG, McElrath MJ, Corey L, Frank I; HVTN 085 Study Team. Miner MD, et al. Among authors: spearman p. EBioMedicine. 2024 Feb;100:104987. doi: 10.1016/j.ebiom.2024.104987. Epub 2024 Feb 1. EBioMedicine. 2024. PMID: 38306894 Free PMC article. Clinical Trial.
Tryptophan-based motifs in the LLP3 Region of the HIV-1 envelope glycoprotein cytoplasmic tail direct trafficking to the endosomal recycling compartment and mediate particle incorporation.
Lerner G, Ding L, Spearman P. Lerner G, et al. Among authors: spearman p. bioRxiv [Preprint]. 2023 Apr 28:2023.04.28.538708. doi: 10.1101/2023.04.28.538708. bioRxiv. 2023. Update in: J Virol. 2023 Oct 31;97(10):e0063123. doi: 10.1128/jvi.00631-23 PMID: 37162911 Free PMC article. Updated. Preprint.
Tocilizumab for Treatment of Children and Young Adults With Severe Acute COVID-19: Experience at a Quaternary-care Children's Hospital.
Teoh Z, Danziger-Isakov L, Courter JD, Frenck RW Jr, Grimley MS, Marsh RA, Paulsen GC, Phillips CL, Spearman P, Chima RS, Schulert GS. Teoh Z, et al. Among authors: spearman p. Pediatr Infect Dis J. 2023 Feb 1;42(2):119-121. doi: 10.1097/INF.0000000000003763. Epub 2022 Oct 29. Pediatr Infect Dis J. 2023. PMID: 36638396 Free PMC article.
Specific binding sites on Rhesus rotavirus capsid protein dictate the method of endocytosis inducing the murine model of biliary atresia.
Temple H, Donnelly B, Mohanty SK, Mowery S, Poling HM, Pasula R, Hartman S, Singh A, Mourya R, Bondoc A, Meller J, Jegga AG, Oyama K, McNeal M, Spearman P, Tiao G. Temple H, et al. Among authors: spearman p. Am J Physiol Gastrointest Liver Physiol. 2024 Aug 1;327(2):G267-G283. doi: 10.1152/ajpgi.00308.2023. Epub 2024 Jun 11. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 38860860 Free article.
Infectivity and Immunogenicity of Live-Attenuated Respiratory Syncytial Virus Vaccines in Human Immunodeficiency Virus-Exposed Uninfected Children.
Kelly MS, Cunningham CK, McFarland EJ, Giganti MJ, Lindsey JC, Perlowski C, Libous JL, Jean-Philippe P, Moye J Jr, Karron RA, Collins PL, Buchholz UJ; International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1114, 2000, 2011, 2012, 2013, and 2018 Study Teams. Kelly MS, et al. Open Forum Infect Dis. 2024 Nov 13;11(12):ofae679. doi: 10.1093/ofid/ofae679. eCollection 2024 Dec. Open Forum Infect Dis. 2024. PMID: 39610407 Free PMC article.
179 results