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O-GlcNAc regulates the mitochondrial integrated stress response by regulating ATF4.
Alghusen IM, Carman MS, Wilkins H, Ephrame SJ, Qiang A, Dias WB, Fedosyuk H, Denson AR, Swerdlow RH, Slawson C. Alghusen IM, et al. Among authors: swerdlow rh. Front Aging Neurosci. 2023 Dec 18;15:1326127. doi: 10.3389/fnagi.2023.1326127. eCollection 2023. Front Aging Neurosci. 2023. PMID: 38192280 Free PMC article.
Traumatic Brain Injury Alters the Trajectory of Age-Related Mitochondrial Change.
Harris JL, Wang X, Christian SK, Novikova L, Kalani A, Hui D, Ferren S, Barbay S, Ortiz JP, Nudo RJ, Brooks WM, Wilkins HM, Chalise P, Michaelis ML, Michaelis EK, Swerdlow RH. Harris JL, et al. Among authors: swerdlow rh. J Alzheimers Dis. 2024;97(4):1793-1806. doi: 10.3233/JAD-231237. J Alzheimers Dis. 2024. PMID: 38306050
Proteome profiling of cerebrospinal fluid using machine learning shows a unique protein signature associated with APOE4 genotype.
Shvetcov A, Thomson S, Cho AN, Wilkins HM, Reed JH, Swerdlow RH, Brown DA; Alzheimer’s Disease Neuroimaging Initiative; Finney CA. Shvetcov A, et al. Among authors: swerdlow rh. bioRxiv [Preprint]. 2024 Jun 16:2024.04.18.590160. doi: 10.1101/2024.04.18.590160. bioRxiv. 2024. Update in: Aging Cell. 2024 Dec 25:e14439. doi: 10.1111/acel.14439 PMID: 38915547 Free PMC article. Updated. Preprint.
O-GlcNAc impacts mitophagy via the PINK1-dependent pathway.
Alghusen IM, Carman MS, Wilkins HM, Strope TA, Gimore C, Fedosyuk H, Shawa J, Ephrame SJ, Denson AR, Wang X, Swerdlow RH, Slawson C. Alghusen IM, et al. Among authors: swerdlow rh. Front Aging Neurosci. 2024 Aug 8;16:1387931. doi: 10.3389/fnagi.2024.1387931. eCollection 2024. Front Aging Neurosci. 2024. PMID: 39175808 Free PMC article.
Inhibiting mtDNA transcript translation alters Alzheimer's disease-associated biology.
Gabrielli AP, Novikova L, Ranjan A, Wang X, Ernst NJ, Abeykoon D, Roberts A, Kopp A, Mansel C, Qiao L, Lysaker CR, Wiedling IW, Wilkins HM, Swerdlow RH. Gabrielli AP, et al. Among authors: swerdlow rh. Alzheimers Dement. 2024 Dec;20(12):8429-8443. doi: 10.1002/alz.14275. Epub 2024 Oct 23. Alzheimers Dement. 2024. PMID: 39441557 Free PMC article.
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[No authors listed] [No authors listed] PMID: 39750923
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[No authors listed] [No authors listed] PMID: 39751518
A multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement.
Macchi Z, Wang Y, Moore D, Katz J, Saperstein D, Walk D, Simpson E, Genge A, Bertorini T, Fernandes JA, Swenson A, Elman L, Dimachkie M, Herbelin L, Miller J, Lu J, Wilkins H, Swerdlow RH, Statland J, Barohn R; Western ALS (WALS) Rasagiline Study Group. Macchi Z, et al. Among authors: swerdlow rh. Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(5-6):345-52. doi: 10.3109/21678421.2015.1026826. Epub 2015 Apr 2. Amyotroph Lateral Scler Frontotemporal Degener. 2015. PMID: 25832828 Free PMC article.
488 results