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352 results

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Page 1
Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis.
Schoenpflug LA, Chatzipli A, Sirinukunwattana K, Richman S, Blake A, Robineau J, Mertz KD, Verrill C, Leedham SJ, Hardy C, Whalley C, Redmond K, Dunne P, Walker S, Beggs AD, McDermott U, Murray GI, Samuel LM, Seymour M, Tomlinson I, Quirke P; S:CORT consortium; Rittscher J, Maughan T, Domingo E, Koelzer VH. Schoenpflug LA, et al. Among authors: dunne p. J Pathol. 2024 Dec 22. doi: 10.1002/path.6376. Online ahead of print. J Pathol. 2024. PMID: 39710952
Targeting the PREX2/RAC1/PI3Kβ Signaling Axis Confers Sensitivity to Clinically Relevant Therapeutic Approaches in Melanoma.
Ford CA, Koludrovic D, Centeno PP, Foth M, Tsonou E, Vlahov N, Sphyris N, Gilroy K, Bull C, Nixon C, Serrels B, Munro AF, Dawson JC, Carragher NO, Pavet V, Hornigold DC, Dunne PD, Downward J, Welch HC, Barry ST, Sansom OJ, Campbell AD. Ford CA, et al. Among authors: dunne pd. Cancer Res. 2024 Dec 5. doi: 10.1158/0008-5472.CAN-23-2814. Online ahead of print. Cancer Res. 2024. PMID: 39636745
Tumor-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signaling.
Leonard NA, Corry SM, Reidy E, Egan H, O'Malley G, Thompson K, McDermott E, O'Neill A, Zakaria N, Egan LJ, Ritter T, Loessner D, Redmond K, Sheehan M, Canney A, Hogan AM, Hynes SO, Treacy O, Dunne PD, Ryan AE. Leonard NA, et al. Among authors: dunne pd. iScience. 2024 Aug 22;27(9):110701. doi: 10.1016/j.isci.2024.110701. eCollection 2024 Sep 20. iScience. 2024. PMID: 39310770 Free PMC article.
Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids.
Naderi-Meshkin H, Wahyu Setyaningsih WA, Yacoub A, Carney G, Cornelius VA, Nelson CA, Kelaini S, Donaghy C, Dunne PD, Amirkhah R, Zampetaki A, Zeng L, Stitt AW, Lois N, Grieve DJ, Margariti A. Naderi-Meshkin H, et al. Among authors: dunne pd. Stem Cells. 2024 Sep 10;42(9):791-808. doi: 10.1093/stmcls/sxae043. Stem Cells. 2024. PMID: 39049437 Free PMC article.
Low coverage whole genome sequencing of low-grade dysplasia strongly predicts colorectal cancer risk in ulcerative colitis.
Al Bakir I, Curtius K, Cresswell GD, Grant HE, Nasreddin N, Smith K, Nowinski S, Guo Q, Belnoue-Davis HL, Fisher J, Clarke T, Kimberley C, Mossner M, Dunne PD, Loughrey MB, Speight A, East JE, Wright NA, Rodriguez-Justo M, Jansen M, Moorghen M, Baker AM, Leedham SJ, Hart AL, Graham TA. Al Bakir I, et al. Among authors: dunne pd. medRxiv [Preprint]. 2024 Jul 8:2024.07.08.24309811. doi: 10.1101/2024.07.08.24309811. medRxiv. 2024. PMID: 39040198 Free PMC article. Preprint.
Stratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signatures.
Mahmood U, Blake A, Rathee S, Samuel L, Murray G, Sebag-Montefiore D, Gollins S, West NP, Begum R, Bach SP, Richman SD, Quirke P, Redmond KL, Salto-Tellez M, Koelzer VH, Leedham SJ, Tomlinson I, Dunne PD, Buffa FM; S:CORT consortium; Maughan TS, Domingo E. Mahmood U, et al. Among authors: dunne pd. Cancer Res Commun. 2024 Jul 1;4(7):1765-1776. doi: 10.1158/2767-9764.CRC-23-0502. Cancer Res Commun. 2024. PMID: 39023969 Free PMC article.
352 results