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Monitoring melanoma patients on treatment reveals a distinct macrophage population driving targeted therapy resistance.
Vasilevska J, Cheng PF, Lehmann J, Ramelyte E, Gómez JM, Dimitriou F, Sella F; TuPro Consortium; Ferretti D, Salas-Bastos A, Jordaan WS, Levesque MP, Dummer R, Sommer L. Vasilevska J, et al. Among authors: levesque mp. Cell Rep Med. 2024 Jul 16;5(7):101611. doi: 10.1016/j.xcrm.2024.101611. Epub 2024 Jun 27. Cell Rep Med. 2024. PMID: 38942020 Free PMC article.
The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.
Zingg D, Debbache J, Schaefer SM, Tuncer E, Frommel SC, Cheng P, Arenas-Ramirez N, Haeusel J, Zhang Y, Bonalli M, McCabe MT, Creasy CL, Levesque MP, Boyman O, Santoro R, Shakhova O, Dummer R, Sommer L. Zingg D, et al. Among authors: levesque mp. Nat Commun. 2015 Jan 22;6:6051. doi: 10.1038/ncomms7051. Nat Commun. 2015. PMID: 25609585 Free article.
Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma.
Cheng PF, Shakhova O, Widmer DS, Eichhoff OM, Zingg D, Frommel SC, Belloni B, Raaijmakers MI, Goldinger SM, Santoro R, Hemmi S, Sommer L, Dummer R, Levesque MP. Cheng PF, et al. Among authors: levesque mp. Genome Biol. 2015 Feb 22;16(1):42. doi: 10.1186/s13059-015-0594-4. Genome Biol. 2015. PMID: 25885555 Free PMC article.
low neurotrophin receptor CD271 regulates phenotype switching in melanoma.
Restivo G, Diener J, Cheng PF, Kiowski G, Bonalli M, Biedermann T, Reichmann E, Levesque MP, Dummer R, Sommer L. Restivo G, et al. Among authors: levesque mp. Nat Commun. 2017 Dec 7;8(1):1988. doi: 10.1038/s41467-017-01573-6. Nat Commun. 2017. PMID: 29215016 Free PMC article.
Methadone-Not a magic bullet in melanoma therapy.
Brüggen MC, Mangana J, Irmisch A, French LE, Levesque MP, Cheng PF, Dummer R. Brüggen MC, et al. Among authors: levesque mp. Exp Dermatol. 2018 Jun;27(6):694-696. doi: 10.1111/exd.13543. Exp Dermatol. 2018. PMID: 29577418 Free article.
EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
Zingg D, Debbache J, Peña-Hernández R, Antunes AT, Schaefer SM, Cheng PF, Zimmerli D, Haeusel J, Calçada RR, Tuncer E, Zhang Y, Bossart R, Wong KK, Basler K, Dummer R, Santoro R, Levesque MP, Sommer L. Zingg D, et al. Among authors: levesque mp. Cancer Cell. 2018 Jul 9;34(1):69-84.e14. doi: 10.1016/j.ccell.2018.06.001. Epub 2018 Jun 28. Cancer Cell. 2018. PMID: 30008323 Free article.
223 results