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Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations.
McCoull W, Thomson C, Braybrooke E, Chan C, Colclough N, Cortés González MA, Cosulich S, Davies NL, Floc'h N, Greenwood R, Hargreaves D, Huang P, Hunt TA, Johnson T, Johnström P, Kettle JG, Kondrashov M, Kostomiris DH, Li S, Lister A, Martin S, McKerrecher D, McLean N, Nissink JWM, Orme JP, Orwig P, Packer MJ, Pearson S, Qin L, Felisberto-Rodrigues C, Savoca A, Schou M, Stokes S, Swaih AM, Talbot S, Tucker MJ, Ward RA, Wadforth E, Wang C, Wilson J, Yang Y. McCoull W, et al. Among authors: wang c. J Med Chem. 2025 Jan 27. doi: 10.1021/acs.jmedchem.4c02811. Online ahead of print. J Med Chem. 2025. PMID: 39869768
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