Kawakita E - Search Results

1

NAD⁺ deficiency plays essential roles in the hyperuricemia of stroke-prone spontaneously hypertensive rat via xanthine dehydrogenase to xanthine oxidase conversion.

Ferdaus SA, Ohara H, Matsuo H, Kawakami K, Takeuchi F, Fujikawa K, Kawakita E, Kato N, Nabika T, Kanasaki K. Ferdaus SA, et al. Among authors: kawakita e. Biochem Biophys Res Commun. 2025 Jan;744:151136. doi: 10.1016/j.bbrc.2024.151136. Epub 2024 Dec 12. Biochem Biophys Res Commun. 2025. PMID: 39708398

2

Inhibition of Dipeptidyl Peptidase-4 Accelerates Epithelial-Mesenchymal Transition and Breast Cancer Metastasis via the CXCL12/CXCR4/mTOR Axis.

Yang F, Takagaki Y, Yoshitomi Y, Ikeda T, Li J, Kitada M, Kumagai A, Kawakita E, Shi S, Kanasaki K, Koya D. Yang F, et al. Among authors: kawakita e. Cancer Res. 2019 Feb 15;79(4):735-746. doi: 10.1158/0008-5472.CAN-18-0620. Epub 2018 Dec 24. Cancer Res. 2019. PMID: 30584072

3

Relevance of Autophagy Induction by Gastrointestinal Hormones: Focus on the Incretin-Based Drug Target and Glucagon.

Kanasaki K, Kawakita E, Koya D. Kanasaki K, et al. Among authors: kawakita e. Front Pharmacol. 2019 May 16;10:476. doi: 10.3389/fphar.2019.00476. eCollection 2019. Front Pharmacol. 2019. PMID: 31156426 Free PMC article. Review.

4

Deficiency in Dipeptidyl Peptidase-4 Promotes Chemoresistance through the CXCL12/CXCR4/mTOR/TGFβ Signaling Pathway in Breast Cancer Cells.

Li S, Fan Y, Kumagai A, Kawakita E, Kitada M, Kanasaki K, Koya D. Li S, et al. Among authors: kawakita e. Int J Mol Sci. 2020 Jan 26;21(3):805. doi: 10.3390/ijms21030805. Int J Mol Sci. 2020. PMID: 31991851 Free PMC article.

5

Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling.

Kawakita E, Yang F, Kumagai A, Takagaki Y, Kitada M, Yoshitomi Y, Ikeda T, Nakamura Y, Ishigaki Y, Kanasaki K, Koya D. Kawakita E, et al. Mol Cancer Res. 2021 Jan;19(1):61-73. doi: 10.1158/1541-7786.MCR-20-0115. Epub 2020 Sep 29. Mol Cancer Res. 2021. PMID: 32994182 Free article.

6

CD26/DPP-4: Type 2 Diabetes Drug Target with Potential Influence on Cancer Biology.

Kawakita E, Koya D, Kanasaki K. Kawakita E, et al. Cancers (Basel). 2021 May 2;13(9):2191. doi: 10.3390/cancers13092191. Cancers (Basel). 2021. PMID: 34063285 Free PMC article. Review.

7

Linagliptin ameliorated cardiac fibrosis and restored cardiomyocyte structure in diabetic mice associated with the suppression of necroptosis.

Adhikari J, Hirai T, Kawakita E, Iwai K, Koya D, Kanasaki K. Adhikari J, et al. Among authors: kawakita e. J Diabetes Investig. 2023 Jul;14(7):844-855. doi: 10.1111/jdi.14017. Epub 2023 Apr 24. J Diabetes Investig. 2023. PMID: 37092329 Free PMC article.

8

Inhibition of Dipeptidyl Peptidase-4 Activates Autophagy to Promote Survival of Breast Cancer Cells via the mTOR/HIF-1α Pathway.

Kawakita E, Yang F, Shi S, Takagaki Y, Koya D, Kanasaki K. Kawakita E, et al. Cancers (Basel). 2023 Sep 12;15(18):4529. doi: 10.3390/cancers15184529. Cancers (Basel). 2023. PMID: 37760498 Free PMC article.

9

Cancer biology in diabetes update: Focusing on antidiabetic drugs.

Kawakita E, Kanasaki K. Kawakita E, et al. J Diabetes Investig. 2024 May;15(5):525-540. doi: 10.1111/jdi.14152. Epub 2024 Mar 8. J Diabetes Investig. 2024. PMID: 38456597 Free PMC article. Review.

10

The PKM2 activator TEPP-46 suppresses cellular senescence in hydrogen peroxide-induced proximal tubular cells and kidney fibrosis in CD-1^db/db mice.

Ishihara SI, Kayes MI, Makino H, Matsuda H, Kumagai A, Hayashi Y, Ferdaus SA, Kawakita E, Koya D, Kanasaki K. Ishihara SI, et al. Among authors: kawakita e. J Diabetes Investig. 2025 Jan 22. doi: 10.1111/jdi.14397. Online ahead of print. J Diabetes Investig. 2025. PMID: 39840670 Free article.

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