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Alzheimer's disease clinical variants show distinct neuroinflammatory profiles with neuropathology.
Boon BDC, Frigerio I, de Gooijer D, Morrema THJ, Bol J, Galis-de Graaf Y, Heymans M; Netherlands Brain Bank; Murray ME; Normal Aging Brain Collection Amsterdam; van der Lee SJ, Holstege H, van de Berg WDJ, Jonkman LE, Rozemuller AJM, Bouwman FH, Hoozemans JJM. Boon BDC, et al. Among authors: rozemuller ajm. Neuropathol Appl Neurobiol. 2024 Oct;50(5):e13009. doi: 10.1111/nan.13009. Neuropathol Appl Neurobiol. 2024. PMID: 39400356
Gene-expression profiling of individuals resilient to Alzheimer's disease reveals higher expression of genes related to metallothionein and mitochondrial processes and no changes in the unfolded protein response.
de Vries LE, Jongejan A, Monteiro Fortes J, Balesar R, Rozemuller AJM, Moerland PD, Huitinga I, Swaab DF, Verhaagen J. de Vries LE, et al. Among authors: rozemuller ajm. Acta Neuropathol Commun. 2024 Apr 25;12(1):68. doi: 10.1186/s40478-024-01760-9. Acta Neuropathol Commun. 2024. PMID: 38664739 Free PMC article.
Microstructural integrity of the locus coeruleus and its tracts reflect noradrenergic degeneration in Alzheimer's disease and Parkinson's disease.
Lin CP, Frigerio I, Bol JGJM, Bouwman MMA, Wesseling AJ, Dahl MJ, Rozemuller AJM, van der Werf YD, Pouwels PJW, van de Berg WDJ, Jonkman LE. Lin CP, et al. Among authors: rozemuller ajm. Transl Neurodegener. 2024 Feb 9;13(1):9. doi: 10.1186/s40035-024-00400-5. Transl Neurodegener. 2024. PMID: 38336865 Free PMC article.
Regional differences in synaptic degeneration are linked to alpha-synuclein burden and axonal damage in Parkinson's disease and dementia with Lewy bodies.
Frigerio I, Bouwman MMA, Noordermeer RTGMM, Podobnik E, Popovic M, Timmermans E, Rozemuller AJM, van de Berg WDJ, Jonkman LE. Frigerio I, et al. Among authors: rozemuller ajm. Acta Neuropathol Commun. 2024 Jan 3;12(1):4. doi: 10.1186/s40478-023-01711-w. Acta Neuropathol Commun. 2024. PMID: 38173031 Free PMC article.
152 results