Jörg M - Search Results

1

Development of environmentally biodegradable drugs: what are the key challenges?

Bertram MG, Wong BBM, Kümmerer K, Jörg M. Bertram MG, et al. Among authors: jorg m. Expert Opin Drug Discov. 2024 Dec 24:1-4. doi: 10.1080/17460441.2024.2442746. Online ahead of print. Expert Opin Drug Discov. 2024. PMID: 39705026 No abstract available.

2

Click Chemistry: Reaction Rates and Their Suitability for Biomedical Applications.

Luu T, Gristwood K, Knight JC, Jörg M. Luu T, et al. Among authors: jorg m. Bioconjug Chem. 2024 Jun 19;35(6):715-731. doi: 10.1021/acs.bioconjchem.4c00084. Epub 2024 May 22. Bioconjug Chem. 2024. PMID: 38775705 Free PMC article. Review.

3

The application of targeted protein degradation technologies to G protein-coupled receptors.

Keen AC, Jörg M, Halls ML. Keen AC, et al. Among authors: jorg m. Br J Pharmacol. 2024 Jul;181(14):2351-2358. doi: 10.1111/bph.16079. Epub 2023 Apr 20. Br J Pharmacol. 2024. PMID: 36965004 Review.

4

Examining the Role of the Linker in Bitopic N⁶-Substituted Adenosine Derivatives Acting as Biased Adenosine A₁ Receptor Agonists.

Awalt JK, Nguyen ATN, Fyfe TJ, Thai BS, White PJ, Christopoulos A, Jörg M, May LT, Scammells PJ. Awalt JK, et al. Among authors: jorg m. J Med Chem. 2022 Jul 14;65(13):9076-9095. doi: 10.1021/acs.jmedchem.2c00320. Epub 2022 Jun 21. J Med Chem. 2022. PMID: 35729775

5

Phenotypic-Based Discovery and Exploration of a Resorufin Scaffold with Activity against Mycobacterium tuberculosis.

Tran E, Cheung CY, Li L, Carter GP, Gable RW, West NP, Kaur A, Gee YS, Cook GM, Baell JB, Jörg M. Tran E, et al. Among authors: jorg m. ChemMedChem. 2024 Dec 16;19(24):e202400482. doi: 10.1002/cmdc.202400482. Epub 2024 Oct 25. ChemMedChem. 2024. PMID: 39248310 Free PMC article.

6

Chemical biology-based approaches to study adenosine A_2A - dopamine D₂ receptor heteromers.

Gregory KJ, Jörg M. Gregory KJ, et al. Among authors: jorg m. Purinergic Signal. 2022 Dec;18(4):395-398. doi: 10.1007/s11302-022-09860-8. Epub 2022 Mar 29. Purinergic Signal. 2022. PMID: 35348986 Free PMC article. No abstract available.

7

The Design, Synthesis, and Evaluation of Novel 9-Arylxanthenedione-Based Allosteric Modulators for the δ-Opioid Receptor.

Deo O, Alvi S, Pham V, Christopoulos A, Thal DM, Jörg M, Capuano B, Valant C, Scammells PJ. Deo O, et al. Among authors: jorg m. J Med Chem. 2022 Sep 22;65(18):12367-12385. doi: 10.1021/acs.jmedchem.2c01061. Epub 2022 Sep 13. J Med Chem. 2022. PMID: 36099150

8

New small molecule fluorescent probes for G protein-coupled receptors: valuable tools for drug discovery.

Conner JW, Poole DP, Jörg M, Veldhuis NA. Conner JW, et al. Among authors: jorg m. Future Med Chem. 2021 Jan;13(1):63-90. doi: 10.4155/fmc-2019-0327. Epub 2020 Dec 15. Future Med Chem. 2021. PMID: 33319586

9

The right tools for the job: the central role for next generation chemical probes and chemistry-based target deconvolution methods in phenotypic drug discovery.

Jörg M, Madden KS. Jörg M, et al. RSC Med Chem. 2021 Mar 24;12(5):646-665. doi: 10.1039/d1md00022e. RSC Med Chem. 2021. PMID: 34124668 Free PMC article. Review.

10

A Structure-Activity Relationship Study of Bitopic N⁶-Substituted Adenosine Derivatives as Biased Adenosine A₁ Receptor Agonists.

Aurelio L, Baltos JA, Ford L, Nguyen ATN, Jörg M, Devine SM, Valant C, White PJ, Christopoulos A, May LT, Scammells PJ. Aurelio L, et al. Among authors: jorg m. J Med Chem. 2018 Mar 8;61(5):2087-2103. doi: 10.1021/acs.jmedchem.8b00047. Epub 2018 Feb 23. J Med Chem. 2018. PMID: 29446948

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