Gao L - Search Results

1

A Self-Assembled Nano-Molecular Glue (Nano-mGlu) Enables GSH/H₂O₂-Triggered Targeted Protein Degradation in Cancer Therapy.

Sun J, Gu M, Peng L, Guo J, Chen P, Wen Y, Feng F, Chen X, Liu T, Chen Y, Lu X, Gao L, Yao SQ, Yuan P. Sun J, et al. Among authors: gao l. J Am Chem Soc. 2024 Dec 20. doi: 10.1021/jacs.4c11003. Online ahead of print. J Am Chem Soc. 2024. PMID: 39703105

2

2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases.

Chen P, Tang G, Zhu C, Sun J, Wang X, Xiang M, Huang H, Wang W, Li L, Zhang ZM, Gao L, Yao SQ. Chen P, et al. Among authors: gao l. J Am Chem Soc. 2023 Feb 12. doi: 10.1021/jacs.2c11595. Online ahead of print. J Am Chem Soc. 2023. PMID: 36774655

3

Small Molecule-Induced Post-Translational Acetylation of Catalytic Lysine of Kinases in Mammalian Cells.

Tang G, Wang X, Huang H, Xu M, Ma X, Miao F, Lu X, Zhang CJ, Gao L, Zhang ZM, Yao SQ. Tang G, et al. Among authors: gao l. J Am Chem Soc. 2024 Aug 28;146(34):23978-23988. doi: 10.1021/jacs.4c07181. Epub 2024 Aug 20. J Am Chem Soc. 2024. PMID: 39162335

4

Comparative proteomic profiling of mammalian cell lysates using phosphopeptide microarrays.

Gao L, Uttamchandani M, Yao SQ. Gao L, et al. Chem Commun (Camb). 2012 Feb 21;48(16):2240-2. doi: 10.1039/c2cc17701c. Epub 2012 Jan 18. Chem Commun (Camb). 2012. PMID: 22252530

5

Engineered Cell-Penetrating Peptides for Mitochondrion-Targeted Drug Delivery in Cancer Therapy.

Xiao Q, Dong X, Yang F, Zhou S, Xiang M, Lou L, Yao SQ, Gao L. Xiao Q, et al. Among authors: gao l. Chemistry. 2021 Oct 21;27(59):14721-14729. doi: 10.1002/chem.202102523. Epub 2021 Sep 30. Chemistry. 2021. PMID: 34436802

6

Emerging biosensing and transducing techniques for potential applications in point-of-care diagnostics.

Qin J, Wang W, Gao L, Yao SQ. Qin J, et al. Among authors: gao l. Chem Sci. 2022 Jan 11;13(10):2857-2876. doi: 10.1039/d1sc06269g. eCollection 2022 Mar 9. Chem Sci. 2022. PMID: 35382472 Free PMC article. Review.

7

Cell-Active, Reversible, and Irreversible Covalent Inhibitors That Selectively Target the Catalytic Lysine of BCR-ABL Kinase.

Chen P, Sun J, Zhu C, Tang G, Wang W, Xu M, Xiang M, Zhang CJ, Zhang ZM, Gao L, Yao SQ. Chen P, et al. Among authors: gao l. Angew Chem Int Ed Engl. 2022 Jun 27;61(26):e202203878. doi: 10.1002/anie.202203878. Epub 2022 Apr 29. Angew Chem Int Ed Engl. 2022. PMID: 35438229

8

Cell-active, irreversible covalent inhibitors that selectively target the catalytic lysine of EGFR by using fluorosulfate-based SuFEx chemistry.

Tang G, Wang W, Wang X, Ding K, Ngan SC, Chen JY, Sze SK, Gao L, Yuan P, Lu X, Yao SQ. Tang G, et al. Among authors: gao l. Eur J Med Chem. 2023 Nov 5;259:115671. doi: 10.1016/j.ejmech.2023.115671. Epub 2023 Jul 21. Eur J Med Chem. 2023. PMID: 37499291

9

Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development.

Tang G, Wang W, Zhu C, Huang H, Chen P, Wang X, Xu M, Sun J, Zhang CJ, Xiao Q, Gao L, Zhang ZM, Yao SQ. Tang G, et al. Among authors: gao l. Angew Chem Int Ed Engl. 2024 Mar 18;63(12):e202316394. doi: 10.1002/anie.202316394. Epub 2024 Feb 14. Angew Chem Int Ed Engl. 2024. PMID: 38248139

10

Kinase Inhibition via Small Molecule-Induced Intramolecular Protein Cross-Linking.

Wang X, Sun J, Huang H, Tang G, Chen P, Xiang M, Li L, Zhang ZM, Gao L, Yao SQ. Wang X, et al. Among authors: gao l. Angew Chem Int Ed Engl. 2024 Jul 8;63(28):e202404195. doi: 10.1002/anie.202404195. Epub 2024 Jun 7. Angew Chem Int Ed Engl. 2024. PMID: 38695161

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