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Efficacy of CTLA-4 checkpoint therapy is dependent on IL-21 signaling to mediate cytotoxic reprogramming of PD-1+CD8+ T cells.
Zhang Z, Langenbach M, Sagar S, Fetsch V, Stritzker J, Severa E, Meng K, Winkler F, Rana N, Zoldan K, Godbole I, Solis S, Weber JS, Rafei-Shamsabadi D, Lehr S, Diehl R, Venhoff AC, Voll RE, Buettner N, Neumann-Haefelin C, Boettler T, Hofmann M, Boerries M, Meiss F, Zeiser R, Thimme R, Herati RS, Bengsch B. Zhang Z, et al. Among authors: stritzker j. Nat Immunol. 2025 Jan;26(1):92-104. doi: 10.1038/s41590-024-02027-0. Epub 2024 Dec 19. Nat Immunol. 2025. PMID: 39702858
Engineered soluble, trimerized 4-1BBL variants as potent immunomodulatory agents.
Battin C, De Sousa Linhares A, Leitner J, Grossmann A, Lupinek D, Izadi S, Castilho A, Waidhofer-Söllner P, Grabmeier-Pfistershammer K, Stritzker J, Steinberger P. Battin C, et al. Among authors: stritzker j. Cancer Immunol Immunother. 2023 Sep;72(9):3029-3043. doi: 10.1007/s00262-023-03474-8. Epub 2023 Jun 13. Cancer Immunol Immunother. 2023. PMID: 37310433 Free PMC article.
Drug-Encoded Biomarkers for Monitoring Biological Therapies.
Tsoneva D, Stritzker J, Bedenk K, Zhang Q, Frentzen A, Cappello J, Fischer U, Szalay AA. Tsoneva D, et al. Among authors: stritzker j. PLoS One. 2015 Sep 8;10(9):e0137573. doi: 10.1371/journal.pone.0137573. eCollection 2015. PLoS One. 2015. PMID: 26348361 Free PMC article.
Doxycycline Inducible Melanogenic Vaccinia Virus as Theranostic Anti-Cancer Agent.
Kirscher L, Deán-Ben XL, Scadeng M, Zaremba A, Zhang Q, Kober C, Fehm TF, Razansky D, Ntziachristos V, Stritzker J, Szalay AA. Kirscher L, et al. Among authors: stritzker j. Theranostics. 2015 Jun 15;5(10):1045-57. doi: 10.7150/thno.12533. eCollection 2015. Theranostics. 2015. PMID: 26199644 Free PMC article.
Use of GLV-1h68 for Vaccinia Virotherapy and Monitoring.
Frentzen A, Geissinger U, Tsoneva D, Stritzker J. Frentzen A, et al. Among authors: stritzker j. Methods Mol Biol. 2015;1317:225-37. doi: 10.1007/978-1-4939-2727-2_13. Methods Mol Biol. 2015. PMID: 26072410
PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses.
Ruiz-Hernández E, Hess M, Melen GJ, Theek B, Talelli M, Shi Y, Ozbakir B, Teunissen EA, Ramírez M, Moeckel D, Kiessling F, Storm G, Scheeren HW, Hennink WE, Szalay AA, Stritzker J, Lammers T. Ruiz-Hernández E, et al. Among authors: stritzker j. Polym Chem. 2014 Mar 7;(5):1674-1681. doi: 10.1039/C3PY01097J. Polym Chem. 2014. PMID: 24518685 Free PMC article.
40 results