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Predicting the tumor microenvironment composition and immunotherapy response in non-small cell lung cancer from digital histopathology images.
Patkar S, Chen A, Basnet A, Bixby A, Rajendran R, Chernet R, Faso S, Kumar PA, Desai D, El-Zammar O, Curtiss C, Carello SJ, Nasr MR, Choyke P, Harmon S, Turkbey B, Jamaspishvili T. Patkar S, et al. NPJ Precis Oncol. 2024 Dec 19;8(1):280. doi: 10.1038/s41698-024-00765-w. NPJ Precis Oncol. 2024. PMID: 39702609 Free PMC article.
Deactivation of ligand-receptor interactions enhancing lymphocyte infiltration drives melanoma resistance to Immune Checkpoint Blockade.
Sahni S, Wang B, Wu D, Dhruba SR, Nagy M, Patkar S, Ferreira I, Wang K, Ruppin E. Sahni S, et al. Among authors: patkar s. bioRxiv [Preprint]. 2023 Sep 22:2023.09.20.558683. doi: 10.1101/2023.09.20.558683. bioRxiv. 2023. Update in: Nat Commun. 2024 Oct 14;15(1):8867. doi: 10.1038/s41467-024-52555-4 PMID: 37886558 Free PMC article. Updated. Preprint.
PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR.
Ghosh S, Nataraj NB, Noronha A, Patkar S, Sekar A, Mukherjee S, Winograd-Katz S, Kramarski L, Verma A, Lindzen M, Garcia DD, Green J, Eisenberg G, Gil-Henn H, Basu A, Lender Y, Weiss S, Oren M, Lotem M, Geiger B, Ruppin E, Yarden Y. Ghosh S, et al. Among authors: patkar s. Cell Rep. 2021 May 25;35(8):109181. doi: 10.1016/j.celrep.2021.109181. Cell Rep. 2021. PMID: 34038737 Free PMC article.
UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma.
Wolf Y, Bartok O, Patkar S, Eli GB, Cohen S, Litchfield K, Levy R, Jiménez-Sánchez A, Trabish S, Lee JS, Karathia H, Barnea E, Day CP, Cinnamon E, Stein I, Solomon A, Bitton L, Pérez-Guijarro E, Dubovik T, Shen-Orr SS, Miller ML, Merlino G, Levin Y, Pikarsky E, Eisenbach L, Admon A, Swanton C, Ruppin E, Samuels Y. Wolf Y, et al. Among authors: patkar s. Cell. 2019 Sep 19;179(1):219-235.e21. doi: 10.1016/j.cell.2019.08.032. Epub 2019 Sep 12. Cell. 2019. PMID: 31522890 Free PMC article.
Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma.
Kalaora S, Wolf Y, Feferman T, Barnea E, Greenstein E, Reshef D, Tirosh I, Reuben A, Patkar S, Levy R, Quinkhardt J, Omokoko T, Qutob N, Golani O, Zhang J, Mao X, Song X, Bernatchez C, Haymaker C, Forget MA, Creasy C, Greenberg P, Carter BW, Cooper ZA, Rosenberg SA, Lotem M, Sahin U, Shakhar G, Ruppin E, Wargo JA, Friedman N, Admon A, Samuels Y. Kalaora S, et al. Among authors: patkar s. Cancer Discov. 2018 Nov;8(11):1366-1375. doi: 10.1158/2159-8290.CD-17-1418. Epub 2018 Sep 12. Cancer Discov. 2018. PMID: 30209080 Free PMC article.
297 results