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Pathogenic mitochondrial DNA variants are associated with response to anti-VEGF therapy in ovarian cancer PDX models.
Boso D, Piga I, Trento C, Minuzzo S, Angi E, Iommarini L, Lazzarini E, Caporali L, Fiorini C, D'Angelo L, De Luise M, Kurelac I, Fassan M, Porcelli AM, Navaglia F, Billato I, Esposito G, Gasparre G, Romualdi C, Indraccolo S. Boso D, et al. Among authors: iommarini l. J Exp Clin Cancer Res. 2024 Dec 19;43(1):325. doi: 10.1186/s13046-024-03239-w. J Exp Clin Cancer Res. 2024. PMID: 39702370 Free PMC article.
A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.
Gasparre G, Kurelac I, Capristo M, Iommarini L, Ghelli A, Ceccarelli C, Nicoletti G, Nanni P, De Giovanni C, Scotlandi K, Betts CM, Carelli V, Lollini PL, Romeo G, Rugolo M, Porcelli AM. Gasparre G, et al. Among authors: iommarini l. Cancer Res. 2011 Oct 1;71(19):6220-9. doi: 10.1158/0008-5472.CAN-11-1042. Epub 2011 Aug 18. Cancer Res. 2011. PMID: 21852384
Pathogenic Mitochondrial DNA Mutation Load Inversely Correlates with Malignant Features in Familial Oncocytic Parathyroid Tumors Associated with Hyperparathyroidism-Jaw Tumor Syndrome.
De Luise M, Iommarini L, Marchio L, Tedesco G, Coadă CA, Repaci A, Turchetti D, Tardio ML, Salfi N, Pagotto U, Kurelac I, Porcelli AM, Gasparre G. De Luise M, et al. Among authors: iommarini l. Cells. 2021 Oct 28;10(11):2920. doi: 10.3390/cells10112920. Cells. 2021. PMID: 34831144 Free PMC article.
Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer.
De Luise M, Sollazzo M, Lama E, Coadă CA, Bressi L, Iorio M, Cavina B, D'Angelo L, Milioni S, Marchio L, Miglietta S, Coluccelli S, Tedesco G, Ghelli A, Lemma S, Perrone AM, Kurelac I, Iommarini L, Porcelli AM, Gasparre G. De Luise M, et al. Among authors: iommarini l. Sci Rep. 2022 May 16;12(1):8020. doi: 10.1038/s41598-022-11620-y. Sci Rep. 2022. PMID: 35577908 Free PMC article.
A comprehensive characterization of mitochondrial DNA mutations in glioblastoma multiforme.
Vidone M, Clima R, Santorsola M, Calabrese C, Girolimetti G, Kurelac I, Amato LB, Iommarini L, Trevisan E, Leone M, Soffietti R, Morra I, Faccani G, Attimonelli M, Porcelli AM, Gasparre G. Vidone M, et al. Among authors: iommarini l. Int J Biochem Cell Biol. 2015 Jun;63:46-54. doi: 10.1016/j.biocel.2015.01.027. Epub 2015 Feb 7. Int J Biochem Cell Biol. 2015. PMID: 25668474
Targeting respiratory complex I to prevent the Warburg effect.
Vatrinet R, Iommarini L, Kurelac I, De Luise M, Gasparre G, Porcelli AM. Vatrinet R, et al. Among authors: iommarini l. Int J Biochem Cell Biol. 2015 Jun;63:41-5. doi: 10.1016/j.biocel.2015.01.017. Epub 2015 Feb 7. Int J Biochem Cell Biol. 2015. PMID: 25668477 Review.
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