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Protocol for CRISPR-Cas9-mediated induction of KMT2A rearrangements in cell line and umbilical cord blood hematopoietic stem and progenitor cells.
Benz T, Larghero P, Meyer C, Müller M, Brüggmann D, Hentrich AE, Louwen F, Erkner E, Fitzel R, Schneidawind C, Marschalek R. Benz T, et al. Among authors: marschalek r. STAR Protoc. 2024 Dec 17;6(1):103481. doi: 10.1016/j.xpro.2024.103481. Online ahead of print. STAR Protoc. 2024. PMID: 39700011 Free article.
Erratum to: Genomic breakpoint-specific monitoring of measurable residual disease in pediatric non-standard risk acute myeloid leukemia.
Maurer-Granofszky M, Köhrer S, Fischer S, Schumich A, Nebral K, Larghero P, Meyer C, Mecklenbräuker A, Mühlegger N, Marschalek R, Haas OA, Panzer-Grümayer R, Dworzak MN. Maurer-Granofszky M, et al. Among authors: marschalek r. Haematologica. 2024 Jul 1;109(7):2379-2381. doi: 10.3324/haematol.2024.285153. Haematologica. 2024. PMID: 38946650 Free PMC article. No abstract available.
The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells.
Reisbeck L, Linder B, Tascher G, Bozkurt S, Weber KJ, Herold-Mende C, van Wijk SJL, Marschalek R, Schaefer L, Münch C, Kögel D. Reisbeck L, et al. Among authors: marschalek r. Am J Physiol Cell Physiol. 2023 Dec 1;325(6):C1451-C1469. doi: 10.1152/ajpcell.00293.2023. Epub 2023 Oct 30. Am J Physiol Cell Physiol. 2023. PMID: 37899749 Free article.
The interferon-regulated host factor hnRNPA0 modulates HIV-1 production by interference with LTR activity, mRNA trafficking, and programmed ribosomal frameshifting.
Roesmann F, Sertznig H, Klaassen K, Wilhelm A, Heininger D, Heß S, Elsner C, Marschalek R, Santiago ML, Esser S, Sutter K, Dittmer U, Widera M. Roesmann F, et al. Among authors: marschalek r. J Virol. 2024 Jul 23;98(7):e0053424. doi: 10.1128/jvi.00534-24. Epub 2024 Jun 20. J Virol. 2024. PMID: 38899932 Free PMC article.
NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression.
Lopez-Millan B, Rubio-Gayarre A, Vinyoles M, Trincado JL, Fraga MF, Fernandez-Fuentes N, Guerrero-Murillo M, Martinez A, Velasco-Hernandez T, Falgàs A, Panisello C, Valcarcel G, Sardina JL, López-Martí P, Javierre BM, Del Valle-Pérez B, García de Herreros A, Locatelli F, Pieters R, Bardini M, Cazzaniga G, Rodríguez-Manzaneque JC, Hanewald T, Marschalek R, Milne TA, Stam RW, Tejedor JR, Menendez P, Bueno C. Lopez-Millan B, et al. Among authors: marschalek r. Blood. 2024 Nov 7;144(19):2002-2017. doi: 10.1182/blood.2023022050. Blood. 2024. PMID: 39093982
Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients.
Hovorkova L, Winkowska L, Skorepova J, Krumbholz M, Benesova A, Polivkova V, Alten J, Bardini M, Meyer C, Kim R, Trahair TN, Clappier E, Chiaretti S, Henderson M, Sutton R, Sramkova L, Stary J, Polakova KM, Marschalek R, Metzler M, Cazzaniga G, Cario G, Trka J, Zaliova M, Zuna J. Hovorkova L, et al. Among authors: marschalek r. Mol Cancer. 2024 Jul 5;23(1):138. doi: 10.1186/s12943-024-02053-4. Mol Cancer. 2024. PMID: 38970095 Free PMC article.
259 results