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Page 1
HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling.
Otoničar J, Lazareva O, Mallm JP, Simovic-Lorenz M, Philippos G, Sant P, Parekh U, Hammann L, Li A, Yildiz U, Marttinen M, Zaugg J, Noh KM, Stegle O, Ernst A. Otoničar J, et al. Among authors: simovic lorenz m. Genome Biol. 2024 Dec 18;25(1):316. doi: 10.1186/s13059-024-03450-0. Genome Biol. 2024. PMID: 39696535 Free PMC article.
Spatio-temporal transcriptomics of chromothriptic SHH-medulloblastoma identifies multiple genetic clones that resist treatment and drive relapse.
Kats I, Simovic-Lorenz M, Schreiber HS, Sant P, Mallm JP, Körber V, Li A, Velmurugan P, Heuer S, Kües L, Devens F, Sill M, Jugold M, Moustafa M, Abdollahi A, Winkler F, Korshunov A, Pfister SM, Stegle O, Ernst A. Kats I, et al. Among authors: simovic lorenz m. Nat Commun. 2024 Nov 29;15(1):10370. doi: 10.1038/s41467-024-54709-w. Nat Commun. 2024. PMID: 39609432 Free PMC article.
Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Smirnov P, Przybilla MJ, Simovic-Lorenz M, Parra RG, Susak H, Ratnaparkhe M, Wong JK, Körber V, Mallm JP, Philippos G, Sill M, Kolb T, Kumar R, Casiraghi N, Okonechnikov K, Ghasemi DR, Maaß KK, Pajtler KW, Jauch A, Korshunov A, Höfer T, Zapatka M, Pfister SM, Huber W, Stegle O, Ernst A. Smirnov P, et al. Among authors: simovic lorenz m. Nat Commun. 2024 Nov 23;15(1):10183. doi: 10.1038/s41467-024-54547-w. Nat Commun. 2024. PMID: 39580568 Free PMC article.
Chromothripsis in cancer.
Simovic-Lorenz M, Ernst A. Simovic-Lorenz M, et al. Nat Rev Cancer. 2024 Nov 15. doi: 10.1038/s41568-024-00769-5. Online ahead of print. Nat Rev Cancer. 2024. PMID: 39548283 Review.