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Elafibranor upregulates the EMT-inducer S100A4 via PPARβ/δ.
Zhang M, Barroso E, Ruart M, Peña L, Peyman M, Aguilar-Recarte D, Montori-Grau M, Rada P, Cugat C, Montironi C, Zarei M, Jurado-Aguilar J, Camins A, Balsinde J, Valverde ÁM, Wahli W, Palomer X, Vázquez-Carrera M. Zhang M, et al. Among authors: wahli w. Biomed Pharmacother. 2023 Nov;167:115623. doi: 10.1016/j.biopha.2023.115623. Epub 2023 Sep 30. Biomed Pharmacother. 2023. PMID: 37783154 Free article.
PPARβ/δ prevents inflammation and fibrosis during diabetic cardiomyopathy.
Rostami A, Palomer X, Pizarro-Delgado J, Barroso E, Valenzuela-Alcaraz B, Crispi F, Nistal JF, Hurlé MA, García R, Wahli W, Vázquez-Carrera M. Rostami A, et al. Among authors: wahli w. Pharmacol Res. 2024 Dec;210:107515. doi: 10.1016/j.phrs.2024.107515. Epub 2024 Nov 20. Pharmacol Res. 2024. PMID: 39577755 Free article.
Striking a gut-liver balance for the antidiabetic effects of metformin.
Barroso E, Montori-Grau M, Wahli W, Palomer X, Vázquez-Carrera M. Barroso E, et al. Among authors: wahli w. Trends Pharmacol Sci. 2023 Jul;44(7):457-473. doi: 10.1016/j.tips.2023.04.004. Epub 2023 May 13. Trends Pharmacol Sci. 2023. PMID: 37188578 Review.
Increased hepatic gluconeogenesis and type 2 diabetes mellitus.
Barroso E, Jurado-Aguilar J, Wahli W, Palomer X, Vázquez-Carrera M. Barroso E, et al. Among authors: wahli w. Trends Endocrinol Metab. 2024 Dec;35(12):1062-1077. doi: 10.1016/j.tem.2024.05.006. Epub 2024 May 29. Trends Endocrinol Metab. 2024. PMID: 38816269 Review.
The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD.
Low ZS, Chua D, Cheng HS, Tee R, Tan WR, Ball C, Sahib NBE, Ng SS, Qu J, Liu Y, Hong H, Cai C, Rao NCL, Wee A, Muthiah MD, Bichler Z, Mickelson B, Kong MS, Tay VS, Yan Z, Chen J, Ng AS, Yip YS, Vos MIG, Tan NA, Lim DL, Lim DXE, Chittezhath M, Yaligar J, Verma SK, Poptani H, Guan XL, Velan SS, Ali Y, Li L, Tan NS, Wahli W. Low ZS, et al. Among authors: wahli w. Adv Sci (Weinh). 2024 Sep;11(35):e2404326. doi: 10.1002/advs.202404326. Epub 2024 Jul 1. Adv Sci (Weinh). 2024. PMID: 38952069 Free PMC article.
345 results