Sampson J - Search Results

1

Targeting ERBB3 and AKT to overcome adaptive resistance in EML4-ALK-driven non-small cell lung cancer.

Sampson J, Ju HM, Zhang N, Yeoh S, Choi J, Bayliss R. Sampson J, et al. Cell Death Dis. 2024 Dec 18;15(12):912. doi: 10.1038/s41419-024-07272-7. Cell Death Dis. 2024. PMID: 39695132 Free PMC article.

2

Phase-separated foci of EML4-ALK facilitate signalling and depend upon an active kinase conformation.

Sampson J, Richards MW, Choi J, Fry AM, Bayliss R. Sampson J, et al. EMBO Rep. 2021 Dec 6;22(12):e53693. doi: 10.15252/embr.202153693. Epub 2021 Oct 18. EMBO Rep. 2021. PMID: 34661367 Free PMC article.

3

EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity.

Lucken K, O'Regan L, Choi J, Sampson J, Pashley SL, Bayliss R, Khan S, Fry AM. Lucken K, et al. Among authors: sampson j. Mol Cancer Res. 2022 Jun 3;20(6):854-866. doi: 10.1158/1541-7786.MCR-21-1010. Mol Cancer Res. 2022. PMID: 35656694 Free PMC article.

4

EML4-ALK biology and drug resistance in non-small cell lung cancer: a new phase of discoveries.

Elshatlawy M, Sampson J, Clarke K, Bayliss R. Elshatlawy M, et al. Among authors: sampson j. Mol Oncol. 2023 Jun;17(6):950-963. doi: 10.1002/1878-0261.13446. Epub 2023 May 15. Mol Oncol. 2023. PMID: 37149843 Free PMC article. Review.

5

ALKing the flames of lung cancer immunosensitivity.

Bayliss R, Sarnowska E, Yeoh S, Sampson J. Bayliss R, et al. Among authors: sampson j. Mol Oncol. 2023 Nov;17(11):2218-2220. doi: 10.1002/1878-0261.13533. Epub 2023 Oct 12. Mol Oncol. 2023. PMID: 37795653 Free PMC article.

6

HER3 overexpression: a predictive marker for poor prognosis in advanced ALK-positive non-small cell lung cancer treated with ALK inhibitors.

Kim M, Ju HM, Song JY, Sampson J, Bayliss R, Choi J. Kim M, et al. Among authors: sampson j. Transl Lung Cancer Res. 2024 Feb 29;13(2):321-333. doi: 10.21037/tlcr-23-804. Epub 2024 Feb 28. Transl Lung Cancer Res. 2024. PMID: 38496685 Free PMC article.

7

A Polytherapy Strategy Using Vincristine and ALK Inhibitors to Sensitise EML4-ALK-Positive NSCLC.

Sampson J, Ju HM, Song JY, Fry AM, Bayliss R, Choi J. Sampson J, et al. Cancers (Basel). 2022 Feb 2;14(3):779. doi: 10.3390/cancers14030779. Cancers (Basel). 2022. PMID: 35159046 Free PMC article.

8

Hsp72 and Nek6 Cooperate to Cluster Amplified Centrosomes in Cancer Cells.

Sampson J, O'Regan L, Dyer MJS, Bayliss R, Fry AM. Sampson J, et al. Cancer Res. 2017 Sep 15;77(18):4785-4796. doi: 10.1158/0008-5472.CAN-16-3233. Epub 2017 Jul 18. Cancer Res. 2017. PMID: 28720575 Free article.

9

Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release.

Mukherjee M, Sabir S, O'Regan L, Sampson J, Richards MW, Huguenin-Dezot N, Ault JR, Chin JW, Zhuravleva A, Fry AM, Bayliss R. Mukherjee M, et al. Among authors: sampson j. Sci Signal. 2018 Aug 14;11(543):eaao2464. doi: 10.1126/scisignal.aao2464. Sci Signal. 2018. PMID: 30108182 Free PMC article.

10

Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression.

O'Regan L, Sampson J, Richards MW, Knebel A, Roth D, Hood FE, Straube A, Royle SJ, Bayliss R, Fry AM. O'Regan L, et al. Among authors: sampson j. J Cell Biol. 2015 May 11;209(3):349-58. doi: 10.1083/jcb.201409151. Epub 2015 May 4. J Cell Biol. 2015. PMID: 25940345 Free PMC article.

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