Zhao Q - Search Results

1

The study of halogen effect on the reactivity of the serine-targeting covalent warheads.

Gai C, Zhang Y, Zhang S, Hu X, Song YQ, Zhuang X, Chai X, Zou Y, Ge GB, Zhao Q. Gai C, et al. Among authors: zhao q. Front Chem. 2024 Dec 3;12:1504453. doi: 10.3389/fchem.2024.1504453. eCollection 2024. Front Chem. 2024. PMID: 39691824 Free PMC article.

2

Advanced approaches of developing targeted covalent drugs.

Gai C, Harnor SJ, Zhang S, Cano C, Zhuang C, Zhao Q. Gai C, et al. Among authors: zhao q. RSC Med Chem. 2022 Oct 11;13(12):1460-1475. doi: 10.1039/d2md00216g. eCollection 2022 Dec 14. RSC Med Chem. 2022. PMID: 36561076 Free PMC article. Review.

3

Cyclic Peptide Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Design, Synthesis, and In Vivo Treatment of Acute Lung Injury.

Zou J, Yan J, Lu Y, Yu Z, Zhang K, Han Q, Han D, Gai C, Chai X, Zhao Q, Zhuang C, Zou Y. Zou J, et al. Among authors: zhao q. J Med Chem. 2024 Mar 28;67(6):4889-4903. doi: 10.1021/acs.jmedchem.4c00065. Epub 2024 Mar 14. J Med Chem. 2024. PMID: 38485922

4

Comprehensive exploration of isocitrate dehydrogenase (IDH) mutations: Tumorigenesis, drug discovery, and covalent inhibitor advances.

Gai C, Zeng H, Xu H, Chai X, Zou Y, Zhuang C, Ge G, Zhao Q. Gai C, et al. Among authors: zhao q. Eur J Med Chem. 2025 Jan 15;282:117041. doi: 10.1016/j.ejmech.2024.117041. Epub 2024 Nov 15. Eur J Med Chem. 2025. PMID: 39591851 Review.

5

Rational Optimizations of the Marine-Derived Peptide Sungsanpin as Novel Inhibitors of Cell Invasion.

Li A, Zou J, Zhuo X, Chen S, Chai X, Gai C, Li X, Zhao Q, Zou Y. Li A, et al. Among authors: zhao q. Chem Biodivers. 2023 Feb;20(2):e202201221. doi: 10.1002/cbdv.202201221. Epub 2023 Jan 30. Chem Biodivers. 2023. PMID: 36651671

6

SOS1-inspired hydrocarbon-stapled peptide as a pan-Ras inhibitor.

Li A, Li X, Zou J, Zhuo X, Chen S, Chai X, Gai C, Xu W, Zhao Q, Zou Y. Li A, et al. Among authors: zhao q. Bioorg Chem. 2023 Jun;135:106500. doi: 10.1016/j.bioorg.2023.106500. Epub 2023 Mar 25. Bioorg Chem. 2023. PMID: 37003134

7

Further structural optimization and SAR study of sungsanpin derivatives as cell-invasion inhibitors.

Chen S, Zhang K, Zou J, Yu Z, Gai C, Chai X, Zhao Q, Zou Y. Chen S, et al. Among authors: zhao q. Bioorg Med Chem Lett. 2024 Feb 1;99:129627. doi: 10.1016/j.bmcl.2024.129627. Epub 2024 Jan 23. Bioorg Med Chem Lett. 2024. PMID: 38272189

8

Discovery of dibenzylbutane lignan LCA derivatives as potent anti-inflammatory agents.

Wang Z, Zhang J, Gai C, Wang J, Zhuo X, Song Y, Zou Y, Zhang P, Hou G, Meng Q, Zhao Q, Chai X. Wang Z, et al. Among authors: zhao q. RSC Med Chem. 2024 Apr 23;15(6):2114-2126. doi: 10.1039/d4md00053f. eCollection 2024 Jun 19. RSC Med Chem. 2024. PMID: 38911165

9

Correction: Discovery of dibenzylbutane lignan LCA derivatives as potent anti-inflammatory agents.

Wang Z, Zhang J, Gai C, Wang J, Zhuo X, Song Y, Zou Y, Zhang P, Hou G, Meng Q, Zhao Q, Chai X. Wang Z, et al. Among authors: zhao q. RSC Med Chem. 2024 Jun 17;15(7):2570-2571. doi: 10.1039/d4md90023e. eCollection 2024 Jul 17. RSC Med Chem. 2024. PMID: 39026649 Free PMC article.

10

New triazole derivatives as antifungal agents: synthesis via click reaction, in vitro evaluation and molecular docking studies.

Zou Y, Zhao Q, Liao J, Hu H, Yu S, Chai X, Xu M, Wu Q. Zou Y, et al. Among authors: zhao q. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2959-62. doi: 10.1016/j.bmcl.2012.02.042. Epub 2012 Feb 23. Bioorg Med Chem Lett. 2012. PMID: 22437114

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