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Synovial innate immune exhaustion is associated with worse pain in knee osteoarthritis.
Philpott HT, Birmingham TB, Blackler G, Klapak JD, Knights AJ, Farrell EC, Fiset B, Walsh LA, Giffin JR, Vasarhelyi EM, MacDonald SJ, Lanting BA, Maerz T, Appleton CT; WOREO Knee Study Group. Philpott HT, et al. Among authors: knights aj. Arthritis Rheumatol. 2024 Dec 17. doi: 10.1002/art.43089. Online ahead of print. Arthritis Rheumatol. 2024. PMID: 39690716
Signaling through the nicotinic acetylcholine receptor in the liver protects against the development of metabolic dysfunction-associated steatohepatitis.
Jun H, Liu S, Knights AJ, Zhu K, Ma Y, Gong J, Lenhart AE, Peng X, Huang Y, Ginder JP, Downie CH, Ramos ET, Kullander K, Kennedy RT, Xu XZS, Wu J. Jun H, et al. Among authors: knights aj. PLoS Biol. 2024 Jul 19;22(7):e3002728. doi: 10.1371/journal.pbio.3002728. eCollection 2024 Jul. PLoS Biol. 2024. PMID: 39028754 Free PMC article.
Publisher Correction: UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.
Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights AJ, Pardo M, Yu L, Choudhary JS, Metzakopian E, Iyer V, Yun H, Park N, Varela I, Bautista R, Collord G, Dovey O, Garyfallos DA, De Braekeleer E, Kondo S, Cooper J, Göttgens B, Bullinger L, Northcott PA, Adams D, Vassiliou GS, Huntly BJP. Gozdecka M, et al. Among authors: knights aj. Nat Genet. 2022 Jul;54(7):1062. doi: 10.1038/s41588-022-01060-9. Nat Genet. 2022. PMID: 35701672 No abstract available.
Robust temporal map of human in vitro myelopoiesis using single-cell genomics.
Alsinet C, Primo MN, Lorenzi V, Bello E, Kelava I, Jones CP, Vilarrasa-Blasi R, Sancho-Serra C, Knights AJ, Park JE, Wyspianska BS, Trynka G, Tough DF, Bassett A, Gaffney DJ, Alvarez-Errico D, Vento-Tormo R. Alsinet C, et al. Among authors: knights aj. Nat Commun. 2022 May 24;13(1):2885. doi: 10.1038/s41467-022-30557-4. Nat Commun. 2022. PMID: 35610203 Free PMC article.
Cannabinoid receptor type 2 is upregulated in synovium following joint injury and mediates anti-inflammatory effects in synovial fibroblasts and macrophages.
Rzeczycki P, Rasner C, Lammlin L, Junginger L, Goldman S, Bergman R, Redding S, Knights AJ, Elliott M, Maerz T. Rzeczycki P, et al. Among authors: knights aj. Osteoarthritis Cartilage. 2021 Dec;29(12):1720-1731. doi: 10.1016/j.joca.2021.09.003. Epub 2021 Sep 17. Osteoarthritis Cartilage. 2021. PMID: 34537380 Free PMC article.
49 results