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Circulating lipid profiles are associated with cross-sectional and longitudinal changes of central biomarkers for Alzheimer's disease.
Kim JP, Nho K, Wang T, Huynh K, Arnold M, Risacher SL, Bice PJ, Han X, Kristal BS, Blach C, Baillie R, Kastenmüller G, Meikle PJ, Saykin AJ, Kaddurah-Daouk R; Alzheimer’s Disease Neuroimaging Initiative; Alzheimer’s Disease Metabolomics Consortium. Kim JP, et al. Among authors: meikle pj. medRxiv [Preprint]. 2023 Jun 21:2023.06.12.23291054. doi: 10.1101/2023.06.12.23291054. medRxiv. 2023. PMID: 37398438 Free PMC article. Preprint.
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data.
Jo T, Kim J, Bice P, Huynh K, Wang T, Arnold M, Meikle PJ, Giles C, Kaddurah-Daouk R, Saykin AJ, Nho K; Alzheimer's Disease Metabolomics Consortium (ADMC); Alzheimer's Disease Neuroimaging Initiative (ADNI). Jo T, et al. Among authors: meikle pj. EBioMedicine. 2023 Nov;97:104820. doi: 10.1016/j.ebiom.2023.104820. Epub 2023 Oct 7. EBioMedicine. 2023. PMID: 37806288 Free PMC article.
Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer's disease.
Marshall JPS, Huynh K, Lancaster GI, Ng J, Collins JM, Pernes G, Liang A, Featherby T, Mellet NA, Drew BG, Calkin AC, King AE, Meikle PJ, Febbraio MA, Adlard PA, Henstridge DC. Marshall JPS, et al. Among authors: meikle pj. iScience. 2024 Jan 4;27(2):108800. doi: 10.1016/j.isci.2024.108800. eCollection 2024 Feb 16. iScience. 2024. PMID: 38292430 Free PMC article.
Development and validation of a plasmalogen score as an independent modifiable marker of metabolic health: population based observational studies and a placebo-controlled cross-over study.
Beyene HB, Huynh K, Wang T, Paul S, Cinel M, Mellett NA, Olshansky G, Meikle TG, Watts GF, Hung J, Hui J, Beilby J, Blangero J, Moses EK, Shaw JE, Magliano DJ, Giles C, Meikle PJ. Beyene HB, et al. Among authors: meikle pj, meikle tg. EBioMedicine. 2024 Jul;105:105187. doi: 10.1016/j.ebiom.2024.105187. Epub 2024 Jun 10. EBioMedicine. 2024. PMID: 38861870 Free PMC article.
A lipidomic based metabolic age score captures cardiometabolic risk independent of chronological age.
Wang T, Beyene HB, Yi C, Cinel M, Mellett NA, Olshansky G, Meikle TG, Wu J, Dakic A, Watts GF, Hung J, Hui J, Beilby J, Blangero J, Kaddurah-Daouk R, Salim A, Moses EK, Shaw JE, Magliano DJ, Huynh K, Giles C, Meikle PJ. Wang T, et al. Among authors: meikle pj, meikle tg. EBioMedicine. 2024 Jul;105:105199. doi: 10.1016/j.ebiom.2024.105199. Epub 2024 Jun 20. EBioMedicine. 2024. PMID: 38905750 Free PMC article.
Lipidomic Risk Score to Enhance Cardiovascular Risk Stratification for Primary Prevention.
Wu J, Giles C, Dakic A, Beyene HB, Huynh K, Wang T, Meikle T, Olshansky G, Salim A, Duong T, Watts GF, Hung J, Hui J, Cadby G, Beilby J, Blangero J, Moses EK, Shaw JE, Magliano DJ, Zhu D, Yang JY, Grieve SM, Wilson A, Chow CK, Vernon ST, Gray MP, Figtree GA, Carrington MJ, Inouye M, Marwick TH, Meikle PJ. Wu J, et al. Among authors: meikle pj, meikle t. J Am Coll Cardiol. 2024 Jul 30;84(5):434-446. doi: 10.1016/j.jacc.2024.04.060. J Am Coll Cardiol. 2024. PMID: 39048275 Free article.
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Among authors: meikle pj. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
A Modified Mediterranean Ketogenic Diet mitigates modifiable risk factors of Alzheimer's Disease: a serum and CSF-based metabolic analysis.
Schweickart A, Batra R, Neth BJ, Martino C, Shenhav L, Zhang AR, Shi P, Karu N, Huynh K, Meikle PJ, Schimmel L, Dilmore AH, Blennow K, Zetterberg H, Blach C, Dorrestein PC, Knight R; Alzheimer’s Gut Microbiome Project Consortium; Craft S, Kaddurah-Daouk R, Krumsiek J. Schweickart A, et al. Among authors: meikle pj. medRxiv [Preprint]. 2023 Nov 27:2023.11.27.23298990. doi: 10.1101/2023.11.27.23298990. medRxiv. 2023. Update in: NPJ Metab Health Dis. 2024;2(1):15. doi: 10.1038/s44324-024-00016-3 PMID: 38076824 Free PMC article. Updated. Preprint.
325 results