Burkhart DJ - Search Results

1

The TLR7/8 agonist INI-4001 enhances the immunogenicity of a Powassan virus-like-particle vaccine.

Crawford MW, Abdelwahab WM, Siram K, Parkins CJ, Harrison HF, Osman SR, Schweitzer D, Evans JT, Burkhart DJ, Pinto AK, Brien JD, Smith JL, Hirsch AJ. Crawford MW, et al. Among authors: burkhart dj. bioRxiv [Preprint]. 2024 Dec 3:2024.11.28.625832. doi: 10.1101/2024.11.28.625832. bioRxiv. 2024. PMID: 39677812 Free PMC article. Preprint.

2

Co-Delivery of a Novel Lipidated TLR7/8 Agonist and Hemagglutinin-Based Influenza Antigen Using Silica Nanoparticles Promotes Enhanced Immune Responses.

Abdelwahab WM, Auclair S, Borgogna T, Siram K, Riffey A, Bazin HG, Cottam HB, Hayashi T, Evans JT, Burkhart DJ. Abdelwahab WM, et al. Among authors: burkhart dj. Pharmaceutics. 2024 Jan 13;16(1):107. doi: 10.3390/pharmaceutics16010107. Pharmaceutics. 2024. PMID: 38258117 Free PMC article.

3

Co-Delivery of Novel Synthetic TLR4 and TLR7/8 Ligands Adsorbed to Aluminum Salts Promotes Th1-Mediated Immunity against Poorly Immunogenic SARS-CoV-2 RBD.

Siram K, Lathrop SK, Abdelwahab WM, Tee R, Davison CJ, Partlow HA, Evans JT, Burkhart DJ. Siram K, et al. Among authors: burkhart dj. Vaccines (Basel). 2023 Dec 23;12(1):21. doi: 10.3390/vaccines12010021. Vaccines (Basel). 2023. PMID: 38250834 Free PMC article.

4

A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice.

Miller SM, Crouse B, Hicks L, Amin H, Cole S, Bazin HG, Burkhart DJ, Pravetoni M, Evans JT. Miller SM, et al. Among authors: burkhart dj. NPJ Vaccines. 2023 Jul 10;8(1):97. doi: 10.1038/s41541-023-00694-y. NPJ Vaccines. 2023. PMID: 37429853 Free PMC article.

5

Self-Adjuvanting TLR7/8 Agonist and Fentanyl Hapten Co-Conjugate Achieves Enhanced Protection against Fentanyl Challenge.

Powers N, Massena C, Crouse B, Smith M, Hicks L, Evans JT, Miller S, Pravetoni M, Burkhart D. Powers N, et al. Bioconjug Chem. 2023 Oct 18;34(10):1811-1821. doi: 10.1021/acs.bioconjchem.3c00347. Epub 2023 Sep 27. Bioconjug Chem. 2023. PMID: 37758302 Free PMC article.

6

Adjuvanted Vaccine Induces Functional Antibodies against Pseudomonas aeruginosa Filamentous Bacteriophages.

Román-Cruz VC, Miller SM, Schoener RA, Lukasiewicz C, Schmidt AK, DeBuysscher BL, Burkhart D, Secor PR, Evans JT. Román-Cruz VC, et al. Vaccines (Basel). 2024 Jan 24;12(2):115. doi: 10.3390/vaccines12020115. Vaccines (Basel). 2024. PMID: 38400099 Free PMC article.

7

Intranasal administration of a synthetic TLR4 agonist INI-2004 significantly reduces allergy symptoms following therapeutic administration in a murine model of allergic sensitization.

Jackson KJ, Buhl C, Miller SM, Khalaf JK, Ward J, Sands C, Walsh L, Whitacre M, Burkhart DJ, Bazin-Lee HG, Evans JT. Jackson KJ, et al. Among authors: burkhart dj. Front Immunol. 2024 Jul 23;15:1421758. doi: 10.3389/fimmu.2024.1421758. eCollection 2024. Front Immunol. 2024. PMID: 39108263 Free PMC article.

8

Promotion of Th17 Polarized Immunity via Co-Delivery of Mincle Agonist and Tuberculosis Antigen Using Silica Nanoparticles.

Abdelwahab WM, Le-Vinh B, Riffey A, Hicks L, Buhl C, Ettenger G, Jackson KJ, Weiss AM, Miller S, Ryter K, Evans JT, Burkhart DJ. Abdelwahab WM, et al. Among authors: burkhart dj. ACS Appl Bio Mater. 2024 Jun 17;7(6):3877-3889. doi: 10.1021/acsabm.4c00245. Epub 2024 Jun 4. ACS Appl Bio Mater. 2024. PMID: 38832760

9

Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination.

Dowling DJ, Barman S, Smith AJ, Borriello F, Chaney D, Brightman SE, Melhem G, Brook B, Menon M, Soni D, Schüller S, Siram K, Nanishi E, Bazin HG, Burkhart DJ, Levy O, Evans JT. Dowling DJ, et al. Among authors: burkhart dj. Sci Rep. 2022 Oct 18;12(1):16860. doi: 10.1038/s41598-022-20346-w. Sci Rep. 2022. PMID: 36258023 Free PMC article.

10

Using Dual Toll-like Receptor Agonism to Drive Th1-Biased Response in a Squalene- and α-Tocopherol-Containing Emulsion for a More Effective SARS-CoV-2 Vaccine.

Short KK, Lathrop SK, Davison CJ, Partlow HA, Kaiser JA, Tee RD, Lorentz EB, Evans JT, Burkhart DJ. Short KK, et al. Among authors: burkhart dj. Pharmaceutics. 2022 Jul 12;14(7):1455. doi: 10.3390/pharmaceutics14071455. Pharmaceutics. 2022. PMID: 35890352 Free PMC article.

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