Pepper A - Search Results

1

Systems biology-enabled targeting of NF-κB and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL.

Vareli A, Narayanan HV, Clark H, Jayawant E, Zhou H, Liu Y, Stott L, Simoes F, Hoffmann A, Pepper A, Pepper C, Mitchell S. Vareli A, et al. Among authors: pepper a. bioRxiv [Preprint]. 2024 Dec 5:2024.11.30.626166. doi: 10.1101/2024.11.30.626166. bioRxiv. 2024. PMID: 39677808 Free PMC article. Preprint.

2

NF-kB and the CLL microenvironment.

O'Donnell A, Pepper C, Mitchell S, Pepper A. O'Donnell A, et al. Among authors: pepper a, pepper c. Front Oncol. 2023 Mar 30;13:1169397. doi: 10.3389/fonc.2023.1169397. eCollection 2023. Front Oncol. 2023. PMID: 37064123 Free PMC article. Review.

3

Computational modeling of DLBCL predicts response to BH3-mimetics.

Cloete I, Smith VM, Jackson RA, Pepper A, Pepper C, Vogler M, Dyer MJS, Mitchell S. Cloete I, et al. Among authors: pepper a, pepper c. NPJ Syst Biol Appl. 2023 Jun 6;9(1):23. doi: 10.1038/s41540-023-00286-5. NPJ Syst Biol Appl. 2023. PMID: 37280330 Free PMC article.

4

NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma.

Jayawant E, Pack A, Clark H, Kennedy E, Ghodke A, Jones J, Pepper C, Pepper A, Mitchell S. Jayawant E, et al. Among authors: pepper a, pepper c. Front Oncol. 2023 Jun 2;13:1181660. doi: 10.3389/fonc.2023.1181660. eCollection 2023. Front Oncol. 2023. PMID: 37333821 Free PMC article.

5

Patient-specific computational models predict prognosis in B cell lymphoma by quantifying pro-proliferative and anti-apoptotic signatures from genetic sequencing data.

Norris R, Jones J, Mancini E, Chevassut T, Simoes FA, Pepper C, Pepper A, Mitchell S. Norris R, et al. Among authors: pepper a, pepper c. Blood Cancer J. 2024 Jul 4;14(1):105. doi: 10.1038/s41408-024-01090-y. Blood Cancer J. 2024. PMID: 38965209 Free PMC article.

6

Targeting the Non-Canonical NF-κB Pathway in Chronic Lymphocytic Leukemia and Multiple Myeloma.

Burley TA, Kennedy E, Broad G, Boyd M, Li D, Woo T, West C, Ladikou EE, Ashworth I, Fegan C, Johnston R, Mitchell S, Mackay SP, Pepper AGS, Pepper C. Burley TA, et al. Among authors: pepper ags, pepper c. Cancers (Basel). 2022 Mar 15;14(6):1489. doi: 10.3390/cancers14061489. Cancers (Basel). 2022. PMID: 35326640 Free PMC article.

7

Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia.

Burley TA, Hesketh A, Bucca G, Kennedy E, Ladikou EE, Towler BP, Mitchell S, Smith CP, Fegan C, Johnston R, Pepper A, Pepper C. Burley TA, et al. Among authors: pepper a, pepper c. Cancers (Basel). 2022 Mar 22;14(7):1600. doi: 10.3390/cancers14071600. Cancers (Basel). 2022. PMID: 35406371 Free PMC article.

8

Dissecting the role of the CXCL12/CXCR4 axis in acute myeloid leukaemia.

Ladikou EE, Chevassut T, Pepper CJ, Pepper AG. Ladikou EE, et al. Br J Haematol. 2020 Jun;189(5):815-825. doi: 10.1111/bjh.16456. Epub 2020 Mar 5. Br J Haematol. 2020. PMID: 32135579 Free article. Review.

9

TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target.

Kennedy E, Coulter E, Halliwell E, Profitos-Peleja N, Walsby E, Clark B, Phillips EH, Burley TA, Mitchell S, Devereux S, Fegan CD, Jones CI, Johnston R, Chevassut T, Schulz R, Seiffert M, Agathanggelou A, Oldreive C, Davies N, Stankovic T, Liloglou T, Pepper C, Pepper AGS. Kennedy E, et al. Among authors: pepper ags, pepper c. Blood. 2021 Jun 3;137(22):3064-3078. doi: 10.1182/blood.2020005964. Blood. 2021. PMID: 33512408 Free PMC article.

10

Novel pyrrolobenzodiazepine benzofused hybrid molecules inhibit NF-κB activity and synergise with bortezomib and ibrutinib in hematological cancers.

Lewis T, Corcoran DB, Thurston DE, Giles PJ, Ashelford K, Walsby EJ, Fegan CD, Pepper AGS, Miraz Rahman K, Pepper C. Lewis T, et al. Haematologica. 2021 Apr 1;106(4):958-967. doi: 10.3324/haematol.2019.238584. Haematologica. 2021. PMID: 32381576 Free PMC article.

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