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143 results

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Page 1
Hierarchical design of pseudosymmetric protein nanocages.
Dowling QM, Park YJ, Fries CN, Gerstenmaier NC, Ols S, Yang EC, Wargacki AJ, Dosey A, Hsia Y, Ravichandran R, Walkey CD, Burrell AL, Veesler D, Baker D, King NP. Dowling QM, et al. Among authors: king np. Nature. 2024 Dec 18. doi: 10.1038/s41586-024-08360-6. Online ahead of print. Nature. 2024. PMID: 39695230
Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad Neuraminidase Inhibition by Human Antibodies.
Lederhofer J, Borst AJ, Nguyen L, Gillespie RA, Williams CJ, Walker EL, Raab JE, Yap C, Ellis D, Creanga A, Tan HX, Do THT, Ravichandran M, McDermott AB, Sage VL, Andrews SF, Graham BS, Wheatley AK, Reed DS, King NP, Kanekiyo M. Lederhofer J, et al. Among authors: king np. bioRxiv [Preprint]. 2024 Dec 3:2024.11.27.625426. doi: 10.1101/2024.11.27.625426. bioRxiv. 2024. PMID: 39677750 Free PMC article. Preprint.
Potent antitumor activity of a designed interleukin-21 mimic.
Chun JH, Lim BS, Roy S, Walsh MJ, Abhiraman GC, Zhangxu K, Atajanova T, Revach OY, Clark EC, Li P, Palin CA, Khanna A, Tower S, Kureshi R, Hoffman MT, Sharova T, Lawless A, Cohen S, Boland GM, Nguyen T, Peprah F, Tello JG, Liu SY, Kim CJ, Shin H, Quijano-Rubio A, Jude KM, Gerben S, Murray A, Heine P, DeWitt M, Ulge UY, Carter L, King NP, Silva DA, Kueh HY, Kalia V, Sarkar S, Jenkins RW, Garcia KC, Leonard WJ, Dougan M, Dougan SK, Baker D. Chun JH, et al. Among authors: king np. bioRxiv [Preprint]. 2024 Dec 7:2024.12.06.626481. doi: 10.1101/2024.12.06.626481. bioRxiv. 2024. PMID: 39677740 Free PMC article. Preprint.
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV.
Chao CW, Sprouse KR, Miranda MC, Catanzaro NJ, Hubbard ML, Addetia A, Stewart C, Brown JT, Dosey A, Valdez A, Ravichandran R, Hendricks GG, Ahlrichs M, Dobbins C, Hand A, McGowan J, Simmons B, Treichel C, Willoughby I, Walls AC, McGuire AT, Leaf EM, Baric RS, Schäfer A, Veesler D, King NP. Chao CW, et al. Among authors: king np. Cell Rep. 2024 Dec 24;43(12):115036. doi: 10.1016/j.celrep.2024.115036. Epub 2024 Dec 6. Cell Rep. 2024. PMID: 39644492 Free article.
Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance.
Dadonaite B, Ahn JJ, Ort JT, Yu J, Furey C, Dosey A, Hannon WW, Vincent Baker AL, Webby RJ, King NP, Liu Y, Hensley SE, Peacock TP, Moncla LH, Bloom JD. Dadonaite B, et al. Among authors: king np. PLoS Biol. 2024 Nov 12;22(11):e3002916. doi: 10.1371/journal.pbio.3002916. eCollection 2024 Nov. PLoS Biol. 2024. PMID: 39531474 Free PMC article.
Computational design of bifaceted protein nanomaterials.
Rankovic S, Carr KD, Decarreau J, Skotheim R, Kibler RD, Ols S, Lee S, Chun JH, Tooley MR, Dauparas J, Eisenach HE, Glögl M, Weidle C, Borst AJ, Baker D, King NP. Rankovic S, et al. Among authors: king np. bioRxiv [Preprint]. 2024 Dec 21:2024.10.18.619149. doi: 10.1101/2024.10.18.619149. bioRxiv. 2024. PMID: 39484564 Free PMC article. Preprint.
Potent neutralization of SARS-CoV-2 variants by RBD nanoparticle and prefusion-stabilized spike immunogens.
Miranda MC, Kepl E, Navarro MJ, Chen C, Johnson M, Sprouse KR, Stewart C, Palser A, Valdez A, Pettie D, Sydeman C, Ogohara C, Kraft JC, Pham M, Murphy M, Wrenn S, Fiala B, Ravichandran R, Ellis D, Carter L, Corti D, Kellam P, Lee K, Walls AC, Veesler D, King NP. Miranda MC, et al. Among authors: king np. NPJ Vaccines. 2024 Oct 8;9(1):184. doi: 10.1038/s41541-024-00982-1. NPJ Vaccines. 2024. PMID: 39379400 Free PMC article.
Mosaic and mixed HIV-1 glycoprotein nanoparticles elicit antibody responses to broadly neutralizing epitopes.
Brinkkemper M, Kerster G, Brouwer PJM, Tran AS, Torres JL, Ettema RA, Nijhuis H, Allen JD, Zhu W, Gao H, Lee WH, Bijl TPL, Snitselaar JL, Burger JA, Bontjer I, Olijhoek W, Ravichandran R, van Breemen MJ, Del Moral-Sánchez I, Derking R, Sliepen K, Ozorowski G, Crispin M, Montefiori DC, Claireaux M, Ward AB, van Gils MJ, King NP, Sanders RW. Brinkkemper M, et al. Among authors: king np. PLoS Pathog. 2024 Oct 3;20(10):e1012558. doi: 10.1371/journal.ppat.1012558. eCollection 2024 Oct. PLoS Pathog. 2024. PMID: 39361585 Free PMC article.
Saponin nanoparticle adjuvants incorporating Toll-like receptor agonists drive distinct immune signatures and potent vaccine responses.
Ou BS, Baillet J, Filsinger Interrante MV, Adamska JZ, Zhou X, Saouaf OM, Yan J, Klich JH, Jons CK, Meany EL, Valdez AS, Carter L, Pulendran B, King NP, Appel EA. Ou BS, et al. Among authors: king np. Sci Adv. 2024 Aug 9;10(32):eadn7187. doi: 10.1126/sciadv.adn7187. Epub 2024 Aug 7. Sci Adv. 2024. PMID: 39110802 Free PMC article.
143 results