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Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change.
Dehkordi SR, Wong IT, Ni J, Luebeck J, Zhu K, Prasad G, Krockenberger L, Xu G, Chowdhury B, Rajkumar U, Caplin A, Muliaditan D, Coruh C, Jin Q, Turner K, Teo SX, Pang AWC, Alexandrov LB, Chua CEL, Furnari FB, Paulson TG, Law JA, Chang HY, Yue F, DasGupta R, Zhao J, Mischel PS, Bafna V. Dehkordi SR, et al. Among authors: jin q. bioRxiv [Preprint]. 2023 Dec 13:2023.12.12.571349. doi: 10.1101/2023.12.12.571349. bioRxiv. 2023. PMID: 38168210 Free PMC article. Preprint.
Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer.
Iyyanki T, Zhang B, Wang Q, Hou Y, Jin Q, Xu J, Yang H, Liu T, Wang X, Song F, Luan Y, Yamashita H, Chien R, Lyu H, Zhang L, Wang L, Warrick J, Raman JD, Meeks JJ, DeGraff DJ, Yue F. Iyyanki T, et al. Among authors: jin q. Genome Biol. 2021 Apr 15;22(1):105. doi: 10.1186/s13059-021-02325-y. Genome Biol. 2021. PMID: 33858483 Free PMC article.
Engineered MED12 mutations drive uterine fibroid-like transcriptional and metabolic programs by altering the 3D genome compartmentalization.
Buyukcelebi K, Chen X, Abdula F, Duval A, Ozturk H, Seker-Polat F, Jin Q, Yin P, Feng Y, Wei JJ, Bulun S, Yue F, Adli M. Buyukcelebi K, et al. Among authors: jin q. Res Sq [Preprint]. 2023 Feb 9:rs.3.rs-2537075. doi: 10.21203/rs.3.rs-2537075/v1. Res Sq. 2023. Update in: Nat Commun. 2023 Jul 10;14(1):4057. doi: 10.1038/s41467-023-39684-y PMID: 36798375 Free PMC article. Updated. Preprint.
Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective.
Mathur R, Wang Q, Schupp PG, Nikolic A, Hilz S, Hong C, Grishanina NR, Kwok D, Stevers NO, Jin Q, Youngblood MW, Stasiak LA, Hou Y, Wang J, Yamaguchi TN, Lafontaine M, Shai A, Smirnov IV, Solomon DA, Chang SM, Hervey-Jumper SL, Berger MS, Lupo JM, Okada H, Phillips JJ, Boutros PC, Gallo M, Oldham MC, Yue F, Costello JF. Mathur R, et al. Among authors: jin q. Cell. 2024 Jan 18;187(2):446-463.e16. doi: 10.1016/j.cell.2023.12.013. Cell. 2024. PMID: 38242087
Subtype-specific 3D genome alteration in acute myeloid leukaemia.
Xu J, Song F, Lyu H, Kobayashi M, Zhang B, Zhao Z, Hou Y, Wang X, Luan Y, Jia B, Stasiak L, Wong JH, Wang Q, Jin Q, Jin Q, Fu Y, Yang H, Hardison RC, Dovat S, Platanias LC, Diao Y, Yang Y, Yamada T, Viny AD, Levine RL, Claxton D, Broach JR, Zheng H, Yue F. Xu J, et al. Among authors: jin q. Nature. 2022 Nov;611(7935):387-398. doi: 10.1038/s41586-022-05365-x. Epub 2022 Oct 26. Nature. 2022. PMID: 36289338 Free PMC article.
A map of cis-regulatory elements and 3D genome structures in zebrafish.
Yang H, Luan Y, Liu T, Lee HJ, Fang L, Wang Y, Wang X, Zhang B, Jin Q, Ang KC, Xing X, Wang J, Xu J, Song F, Sriranga I, Khunsriraksakul C, Salameh T, Li D, Choudhary MNK, Topczewski J, Wang K, Gerhard GS, Hardison RC, Wang T, Cheng KC, Yue F. Yang H, et al. Among authors: jin q. Nature. 2020 Dec;588(7837):337-343. doi: 10.1038/s41586-020-2962-9. Epub 2020 Nov 25. Nature. 2020. PMID: 33239788 Free PMC article.
4,210 results