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Page 1
Spermidine alleviates depression via control of the stress response.
Mackert S, Niemeyer C, Mecdad Y, Ebert T, Bajaj T, Durand S, Hofer SJ, Zellner A, Besteher B, Engelmann J, Gisabella B, Kempf V, Heckmann LA, Laakmann M, Newman EL, Sokn C, Heinz DE, Junglas E, Uribe-Marino A, Magnes C, Klengel C, Müller A, Opriessnig L, Meinitzer A, Lennarz M, Martin KMW, Albatarni R, Brockherde M, Lieb K, Rohner H, Stoffel-Wagner B, Philipsen A, Kuster B, Kölle M, Ressler KJ, Opel N, Schmidt MV, Pantazopoulos H, Müller MB, Kroemer G, Eisenberg T, Hartmann J, Madeo F, Gassen NC. Mackert S, et al. Among authors: junglas e. bioRxiv [Preprint]. 2024 Dec 7:2024.12.04.626625. doi: 10.1101/2024.12.04.626625. bioRxiv. 2024. PMID: 39677641 Free PMC article. Preprint.
Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice.
Stepan J, Heinz DE, Dethloff F, Wiechmann S, Martinelli S, Hafner K, Ebert T, Junglas E, Häusl AS, Pöhlmann ML, Jakovcevski M, Pape JC, Zannas AS, Bajaj T, Hermann A, Ma X, Pavenstädt H, Schmidt MV, Philipsen A, Turck CW, Deussing JM, Rammes G, Robinson AC, Payton A, Wehr MC, Stein V, Murgatroyd C, Kremerskothen J, Kuster B, Wotjak CT, Gassen NC. Stepan J, et al. Among authors: junglas e. Sci Signal. 2024 Apr 30;17(834):eadj6603. doi: 10.1126/scisignal.adj6603. Epub 2024 Apr 30. Sci Signal. 2024. PMID: 38687825
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Hartmann J, Bajaj T, Otten J, Klengel C, Ebert T, Gellner AK, Junglas E, Hafner K, Anderzhanova EA, Tang F, Missig G, Rexrode L, Trussell DT, Li KX, Pöhlmann ML, Mackert S, Geiger TM, Heinz DE, Lardenoije R, Dedic N, McCullough KM, Próchnicki T, Rhomberg T, Martinelli S, Payton A, Robinson AC, Stein V, Latz E, Carlezon WA Jr, Hausch F, Schmidt MV, Murgatroyd C, Berretta S, Klengel T, Pantazopoulos H, Ressler KJ, Gassen NC. Hartmann J, et al. Among authors: junglas e. Nat Commun. 2024 Mar 25;15(1):2635. doi: 10.1038/s41467-024-46953-x. Nat Commun. 2024. PMID: 38528004 Free PMC article.
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Hartmann J, Bajaj T, Otten J, Klengel C, Gellner AK, Junglas E, Hafner K, Anderzhanova EA, Tang F, Missig G, Rexrode L, Li K, Pöhlmann ML, Heinz DE, Lardenoije R, Dedic N, McCullough KM, Próchnicki T, Rhomberg T, Martinelli S, Payton A, Robinson AC, Stein V, Latz E, Carlezon WA, Schmidt MV, Murgatroyd C, Berretta S, Klengel T, Pantazopoulos H, Ressler KJ, Gassen NC. Hartmann J, et al. Among authors: junglas e. bioRxiv [Preprint]. 2023 Apr 3:2023.04.03.534570. doi: 10.1101/2023.04.03.534570. bioRxiv. 2023. Update in: Nat Commun. 2024 Mar 25;15(1):2635. doi: 10.1038/s41467-024-46953-x PMID: 37066393 Free PMC article. Updated. Preprint.