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Page 1
A genetically based computational drug repurposing framework for rapid identification of candidate compounds: application to COVID-19.
Voloudakis G, Lee KM, Vicari JM, Zhang W, Hoagland D, Venkatesh S, Bian J, Anyfantakis M, Wu Z, Rahman S, Gao L, Cho K, Lee JS, Iyengar SK, Luoh SW, Assimes TL, Hoffman GE, tenOever BR, Fullard JF, Lynch JA, Roussos P. Voloudakis G, et al. medRxiv [Preprint]. 2025 Jan 14:2025.01.10.25320348. doi: 10.1101/2025.01.10.25320348. medRxiv. 2025. PMID: 39867394 Free PMC article. Preprint.
Single-Nucleus Atlas of Cell-Type Specific Genetic Regulation in the Human Brain.
Zeng B, Yang H, N M P, Venkatesh S, Mathur D, Auluck P, Bennett DA, Marenco S, Haroutunian V; PsychAD Consortium; Voloudakis G, Lee D, Fullard JF, Bendl J, Girdhar K, Hoffman GE, Roussos P. Zeng B, et al. Among authors: voloudakis g. Res Sq [Preprint]. 2024 Dec 11:rs.3.rs-5368620. doi: 10.21203/rs.3.rs-5368620/v1. Res Sq. 2024. PMID: 39711543 Free PMC article. Preprint.
Plasticity of Human Microglia and Brain Perivascular Macrophages in Aging and Alzheimer's Disease.
Lee D, Vicari JM, Porras C, Spencer C, Pjanic M, Wang X, Kinrot S, Weiler P, Kosoy R, Bendl J, Prashant NM, Psychogyiou K, Malakates P, Hennigan E, Monteiro Fortes J, Zheng S, Therrien K, Mathur D, Kleopoulos SP, Shao Z, Argyriou S, Alvia M, Casey C, Hong A, Beaumont KG, Sebra R, Kellner CP, Bennett DA, Yuan GC, Voloudakis G, Theis FJ, Haroutunian V, Hoffman GE, Fullard JF, Roussos P. Lee D, et al. Among authors: voloudakis g. medRxiv [Preprint]. 2024 Dec 5:2023.10.25.23297558. doi: 10.1101/2023.10.25.23297558. medRxiv. 2024. PMID: 39677435 Free PMC article. Preprint.
Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries.
Gorman BR, Voloudakis G, Igo RP Jr, Kinzy T, Halladay CW, Bigdeli TB, Zeng B, Venkatesh S, Cooke Bailey JN, Crawford DC, Markianos K, Dong F, Schreiner PA, Zhang W; VA Million Veteran Program; International AMD Genomics Consortium (IAMDGC); Hadi T, Anger MD, Stockwell A, Melles RB, Yin J, Choquet H, Kaye R, Patasova K, Patel PJ, Yaspan BL, Jorgenson E, Hysi PG, Lotery AJ, Gaziano JM, Tsao PS, Fliesler SJ, Sullivan JM, Greenberg PB, Wu WC, Assimes TL, Pyarajan S, Roussos P, Peachey NS, Iyengar SK. Gorman BR, et al. Among authors: voloudakis g. Nat Genet. 2024 Dec;56(12):2659-2671. doi: 10.1038/s41588-024-01764-0. Epub 2024 Dec 2. Nat Genet. 2024. PMID: 39623103
A multi-region single nucleus transcriptomic atlas of Parkinson's disease.
N M P, Fullard JF, Clarence T, Mathur D, Casey C, Hennigan E, Alvia M, Krause-Massaguer J, Barreda A, Davis DA, Vontell RT, Garamszegi SP, Vance JM, Sang L, Chatigny M, Vismer D, Landin B, Burstein D, Lee D, Voloudakis G, Berretta S, Haroutunian V, Scott WK, Bendl J, Roussos P. N M P, et al. Among authors: voloudakis g. Sci Data. 2024 Nov 23;11(1):1274. doi: 10.1038/s41597-024-04117-y. Sci Data. 2024. PMID: 39580497 Free PMC article.
Phenotype Scoring of Population Scale Single-Cell Data Dissects Alzheimer's Disease Complexity.
He C, Li AZ, Arachchilage KH, Gupta C, Huang X, Zhao X; PsychAD Consortium; Girdhar K, Voloudakis G, Hoffman GE, Bendl J, Fullard JF, Lee D, Roussos P, Wang D. He C, et al. Among authors: voloudakis g. medRxiv [Preprint]. 2024 Nov 2:2024.11.01.24316586. doi: 10.1101/2024.11.01.24316586. medRxiv. 2024. PMID: 39574856 Free PMC article. Preprint.
Somatic mosaicism in schizophrenia brains reveals prenatal mutational processes.
Maury EA, Jones A, Seplyarskiy V, Nguyen TTL, Rosenbluh C, Bae T, Wang Y, Abyzov A, Khoshkhoo S, Chahine Y, Zhao S, Venkatesh S, Root E, Voloudakis G, Roussos P; Brain Somatic Mosaicism Network‡; Park PJ, Akbarian S, Brennand K, Reilly S, Lee EA, Sunyaev SR, Walsh CA, Chess A. Maury EA, et al. Among authors: voloudakis g. Science. 2024 Oct 11;386(6718):217-224. doi: 10.1126/science.adq1456. Epub 2024 Oct 10. Science. 2024. PMID: 39388546 Free PMC article.
Biological Insights from Schizophrenia-associated Loci in Ancestral Populations.
Bigdeli TB, Chatzinakos C, Bendl J, Barr PB, Venkatesh S, Gorman BR, Clarence T, Genovese G, Iyegbe CO, Peterson RE, Kolokotronis SO, Burstein D, Meyers JL, Li Y, Rajeevan N, Sayward F, Cheung KH; Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS); Consortium on the Genomics of Schizophrenia (COGS); Genomic Psychiatry Cohort (GPC) Investigators; DeLisi LE, Kosten TR, Zhao H, Achtyes E, Buckley P, Malaspina D, Lehrer D, Rapaport MH, Braff DL, Pato MT, Fanous AH, Pato CN; PsychAD Consortium; Cooperative Studies Program (CSP) #572; Million Veteran Program (MVP); Huang GD, Muralidhar S, Michael Gaziano J, Pyarajan S, Girdhar K, Lee D, Hoffman GE, Aslan M, Fullard JF, Voloudakis G, Harvey PD, Roussos P. Bigdeli TB, et al. Among authors: voloudakis g. medRxiv [Preprint]. 2024 Aug 28:2024.08.27.24312631. doi: 10.1101/2024.08.27.24312631. medRxiv. 2024. PMID: 39252912 Free PMC article. Preprint.
61 results