Stříšovský K - Search Results

1

The zymogenic form of SARS-CoV-2 main protease: A discrete target for drug discovery.

Novotný P, Humpolíčková J, Nováková V, Stanchev S, Stříšovský K, Zgarbová M, Weber J, Kryštůfek R, Starková J, Hradilek M, Moravcová A, Günterová J, Bach K, Majer P, Konvalinka J, Majerová T. Novotný P, et al. Among authors: strisovsky k. J Biol Chem. 2024 Dec 13:108079. doi: 10.1016/j.jbc.2024.108079. Online ahead of print. J Biol Chem. 2024. PMID: 39675720 Free article.

2

Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates.

Strisovsky K, Sharpe HJ, Freeman M. Strisovsky K, et al. Mol Cell. 2009 Dec 25;36(6):1048-59. doi: 10.1016/j.molcel.2009.11.006. Mol Cell. 2009. PMID: 20064469 Free PMC article.

3

Monocyclic β-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteases.

Pierrat OA, Strisovsky K, Christova Y, Large J, Ansell K, Bouloc N, Smiljanic E, Freeman M. Pierrat OA, et al. Among authors: strisovsky k. ACS Chem Biol. 2011 Apr 15;6(4):325-35. doi: 10.1021/cb100314y. Epub 2011 Jan 12. ACS Chem Biol. 2011. PMID: 21175222 Free PMC article.

4

The structural basis for catalysis and substrate specificity of a rhomboid protease.

Vinothkumar KR, Strisovsky K, Andreeva A, Christova Y, Verhelst S, Freeman M. Vinothkumar KR, et al. Among authors: strisovsky k. EMBO J. 2010 Nov 17;29(22):3797-809. doi: 10.1038/emboj.2010.243. Epub 2010 Oct 1. EMBO J. 2010. PMID: 20890268 Free PMC article.

5

Systematic mutational analysis of the active-site threonine of HIV-1 proteinase: rethinking the "fireman's grip" hypothesis.

Strisovsky K, Tessmer U, Langner J, Konvalinka J, Kräusslich HG. Strisovsky K, et al. Protein Sci. 2000 Sep;9(9):1631-41. doi: 10.1110/ps.9.9.1631. Protein Sci. 2000. PMID: 11045610 Free PMC article.

6

The murine endogenous retrovirus MIA14 encodes an active aspartic proteinase that is functionally similar to proteinases from D-type retroviruses.

Strísovský K, Smrz D, Fehrmann F, Kräusslich HG, Konvalinka J. Strísovský K, et al. Arch Biochem Biophys. 2002 Feb 15;398(2):261-8. doi: 10.1006/abbi.2001.2728. Arch Biochem Biophys. 2002. PMID: 11831858

7

Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains.

Weber J, Mesters JR, Lepsík M, Prejdová J, Svec M, Sponarová J, Mlcochová P, Skalická K, Strísovský K, Uhlíková T, Soucek M, Machala L, Stanková M, Vondrásek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J. Weber J, et al. Among authors: strisovsky k. J Mol Biol. 2002 Dec 6;324(4):739-54. doi: 10.1016/s0022-2836(02)01139-7. J Mol Biol. 2002. PMID: 12460574

8

Mouse brain serine racemase catalyzes specific elimination of L-serine to pyruvate.

Strísovský K, Jirásková J, Barinka C, Majer P, Rojas C, Slusher BS, Konvalinka J. Strísovský K, et al. FEBS Lett. 2003 Jan 30;535(1-3):44-8. doi: 10.1016/s0014-5793(02)03855-3. FEBS Lett. 2003. PMID: 12560076 Free article.

9

Kinetics of the dimerization of retroviral proteases: the "fireman's grip" and dimerization.

Ingr M, Uhlíková T, Strísovský K, Majerová E, Konvalinka J. Ingr M, et al. Among authors: strisovsky k. Protein Sci. 2003 Oct;12(10):2173-82. doi: 10.1110/ps.03171903. Protein Sci. 2003. PMID: 14500875 Free PMC article.

10

Proteinases of betaretroviruses bind single-stranded nucleic acids through a novel interaction module, the G-patch.

Svec M, Bauerová H, Pichová I, Konvalinka J, Strísovský K. Svec M, et al. Among authors: strisovsky k. FEBS Lett. 2004 Oct 8;576(1-2):271-6. doi: 10.1016/j.febslet.2004.09.010. FEBS Lett. 2004. PMID: 15474050 Free article.

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