Kulkarni O - Search Results

1

Regulation of the blood-brain barrier function by peripheral cues in health and disease.

Devraj K, Kulkarni O, Liebner S. Devraj K, et al. Among authors: kulkarni o. Metab Brain Dis. 2024 Dec 13;40(1):61. doi: 10.1007/s11011-024-01468-8. Metab Brain Dis. 2024. PMID: 39671124 Free PMC article. Review.

2

Pharmacological blockade of HDAC6 attenuates cancer progression by inhibiting IL-1β and modulating immunosuppressive response in OSCC.

Mahale A, Routholla G, Lavanya S, Sharma P, Ghosh B, Kulkarni OP. Mahale A, et al. Int Immunopharmacol. 2024 May 10;132:111921. doi: 10.1016/j.intimp.2024.111921. Epub 2024 Mar 27. Int Immunopharmacol. 2024. PMID: 38547770

3

Development of Benzimidazole-Substituted Spirocyclopropyl Oxindole Derivatives as Cytotoxic Agents: Tubulin Polymerization Inhibition and Apoptosis Inducing Studies.

Sakla AP, Bazaz MR, Mahale A, Sharma P, Valapil DG, Kulkarni OP, Dandekar MP, Shankaraiah N. Sakla AP, et al. ChemMedChem. 2024 Jun 17;19(12):e202400052. doi: 10.1002/cmdc.202400052. Epub 2024 May 3. ChemMedChem. 2024. PMID: 38517377

4

Pharmacological blockade of HDAC3 accelerates diabetic wound healing by regulating macrophage activation.

Karnam K, Sedmaki K, Sharma P, Mahale A, Ghosh B, Kulkarni OP. Karnam K, et al. Life Sci. 2023 May 15;321:121574. doi: 10.1016/j.lfs.2023.121574. Epub 2023 Mar 15. Life Sci. 2023. PMID: 36931496

5

Anti-rheumatoid arthritis potential of Halodule pinifolia: development, characterization and in vivo evaluation of H. pinifolia-based oral suspension and lipid nano-emulsion.

Nessa S, Lavanya S, Routray RK, Chaurasiya A, Kulkarni OP, Begum AS. Nessa S, et al. Inflammopharmacology. 2024 Apr;32(2):1203-1223. doi: 10.1007/s10787-024-01431-0. Epub 2024 Mar 7. Inflammopharmacology. 2024. PMID: 38451395

6

Development and Validation of a Fluorogenic Probe for Lysosomal Zinc Release.

Shukla AK, Mahale A, Choudhary S, Sharma P, Kulkarni OP, Bhattacharya A. Shukla AK, et al. Chembiochem. 2024 Feb 16;25(4):e202300783. doi: 10.1002/cbic.202300783. Epub 2024 Jan 8. Chembiochem. 2024. PMID: 38038368

7

Regioselective synthesis and in vitro cytotoxicity evaluation of 3-thiooxindole derivatives: Tubulin polymerization inhibition and apoptosis inducing studies.

Sakla AP, Panda B, Mahale A, Sharma P, Laxmikeshav K, Ali Khan M, Kulkarni OP, Godugu C, Shankaraiah N. Sakla AP, et al. Bioorg Med Chem. 2023 Jul 15;90:117297. doi: 10.1016/j.bmc.2023.117297. Epub 2023 May 1. Bioorg Med Chem. 2023. PMID: 37343499

8

Triazolo-linked benzimidazoles as tubulin polymerization inhibitors and DNA intercalators: Design, synthesis, cytotoxicity, and docking studies.

Laxmikeshav K, Sayali M, Devabattula G, Valapil DG, Mahale A, Sharma P, George J, Phanindranath R, Godugu C, Kulkarni OP, Nagesh N, Shankaraiah N. Laxmikeshav K, et al. Arch Pharm (Weinheim). 2023 May;356(5):e2200449. doi: 10.1002/ardp.202200449. Epub 2023 Feb 17. Arch Pharm (Weinheim). 2023. PMID: 36807372

9

Discovery of novel substituted (Z)-N'-hydroxy-3-(3-phenylureido)benzimidamide derivatives as multifunctional molecules targeting pathological hallmarks of Alzheimer's disease.

Shankar G, Praveen Kumar C, Yadav M, Ghosh A, Panda SR, Banerjee A, Tiwari A, Rai S, Kumar S, Garg P, Naidu VGM, Kulkarni O, Modi G. Shankar G, et al. Among authors: kulkarni o. Eur J Med Chem. 2024 Dec 15;280:116959. doi: 10.1016/j.ejmech.2024.116959. Epub 2024 Oct 15. Eur J Med Chem. 2024. PMID: 39461036

10

Discovery of novel hybrid tryptamine-rivastigmine molecules as potent AChE and BChE inhibitors exhibiting multifunctional properties for the management of Alzheimer's disease.

Shankar G, Kumar P, Rai S, Ghosh A, Varma T, Wani MA, Kumar S, Mandloi U, Singh GK, Garg P, Kulkarni O, Srikrishna S, Kumar S, Modi G. Shankar G, et al. Among authors: kulkarni o. Eur J Med Chem. 2025 Feb 5;283:117066. doi: 10.1016/j.ejmech.2024.117066. Epub 2024 Nov 27. Eur J Med Chem. 2025. PMID: 39667052

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