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Evaluation of a potent LpxC inhibitor for post-exposure prophylaxis treatment of antibiotic-resistant Burkholderia pseudomallei in a murine infection model.
Heine HS, Purcell BK, Duncan C, Miller L, Craig JE, Chase A, Honour L, Vicchiarelli M, Drusano GL, Zhou P. Heine HS, et al. Among authors: purcell bk. Antimicrob Agents Chemother. 2024 Dec 13:e0129524. doi: 10.1128/aac.01295-24. Online ahead of print. Antimicrob Agents Chemother. 2024. PMID: 39670750 Free article.
Engineered antibodies targeted to bacterial surface integrate effector functions with toxin neutralization to provide superior efficacy against bacterial infections.
Adhikari RP, Alem F, Kemboi D, Kanipakala T, Sherchand SP, Kailasan S, Purcell BK, Heine HS, Russell-Lodrigue K, Etobayeva I, Howell KA, Vu H, Shulenin S, Holtsberg FW, Roy CJ, Hakami RM, Nelson DC, Aman MJ. Adhikari RP, et al. Among authors: purcell bk. medRxiv [Preprint]. 2024 Sep 25:2024.09.23.24313920. doi: 10.1101/2024.09.23.24313920. medRxiv. 2024. PMID: 39398995 Free PMC article. Preprint.
Shiga-Toxin-Producing Strains of Escherichia coli O104:H4 and a Strain of O157:H7, Which Can Cause Human Hemolytic Uremic Syndrome, Differ in Biofilm Formation in the Presence of CO2 and in Their Ability to Grow in a Novel Cell Culture Medium.
Amemiya K, Rozak DA, Dankmeyer JL, Dorman WR, Marchand C, Fetterer DP, Worsham PL, Purcell BK. Amemiya K, et al. Among authors: purcell bk. Microorganisms. 2023 Jul 3;11(7):1744. doi: 10.3390/microorganisms11071744. Microorganisms. 2023. PMID: 37512916 Free PMC article.
Safety and immunogenicity of an inactivated eastern equine encephalitis virus vaccine.
Pierson BC, Cardile AP, Okwesili AC, Downs IL, Reisler RB, Boudreau EF, Kortepeter MG, Koca CD, Ranadive MV, Petitt PL, Kanesa-Thasan N, Rivard RG, Liggett DL, Haller JM, Norris SL, Purcell BK, Pittman PR, Saunders DL, Keshtkar Jahromi M. Pierson BC, et al. Among authors: purcell bk. Vaccine. 2021 May 12;39(20):2780-2790. doi: 10.1016/j.vaccine.2021.03.030. Epub 2021 Apr 19. Vaccine. 2021. PMID: 33888325 Free article.
30 results