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Cilostazol counteracts mitochondrial dysfunction in hepatic encephalopathy rat model: Insights into the role of cAMP/AMPK/SIRT1/ PINK-1/parkin hub and p-CREB /BDNF/ TrkB neuroprotective trajectory.
Gad ES, Aldossary SA, El-Ansary MR, Abd El-Galil MM, Abd-El-Hamid AH, El-Ansary AR, Hassan NF. Gad ES, et al. Among authors: hassan nf. Eur J Pharmacol. 2024 Dec 10;987:177194. doi: 10.1016/j.ejphar.2024.177194. Online ahead of print. Eur J Pharmacol. 2024. PMID: 39667427
The potential role of Tirzepatide as adjuvant therapy in countering colistin-induced nephro and neurotoxicity in rats via modulation of PI3K/p-Akt/GSK3-β/NF-kB p65 hub, shielding against oxidative and endoplasmic reticulum stress, and activation of p-CREB/BDNF/TrkB cascade.
Hassan NF, Ragab D, Ibrahim SG, Abd El-Galil MM, Hassan Abd-El-Hamid A, Hamed DM, Magdy William M, Salem MA. Hassan NF, et al. Int Immunopharmacol. 2024 Jun 30;135:112308. doi: 10.1016/j.intimp.2024.112308. Epub 2024 May 23. Int Immunopharmacol. 2024. PMID: 38788447
Alirocumab boosts antioxidant status and halts inflammation in rat model of sepsis-induced nephrotoxicity via modulation of Nrf2/HO-1, PCSK9/HMGB1/NF-ᴋB/NLRP3 and Fractalkine/CX3CR1 hubs.
Hassan NF, El-Ansary MR, Selim HMRM, Ousman MS, Khattab MS, El-Ansary MRM, Gad ES, Moursi SMM, Gohar A, Gowifel AMH. Hassan NF, et al. Biomed Pharmacother. 2024 Aug;177:116929. doi: 10.1016/j.biopha.2024.116929. Epub 2024 Jun 17. Biomed Pharmacother. 2024. PMID: 38889644 Free article.
Apium extract alleviates indomethacin-induced gastric ulcers in rats via modulating the VEGF and IK-κB/NF-κB p65 signaling pathway: insights from in silico and in vivo investigations.
Abu-Baih DH, Gomaa AA, Abdel-Wahab NM, Abdelaleem ER, Zaher AMA, Hassan NF, Bringmann G, Abdelmohsen UR, Altemani FH, Algehainy NA, Mokhtar FA, Abdelwahab MF. Abu-Baih DH, et al. Among authors: hassan nf. BMC Complement Med Ther. 2024 Feb 14;24(1):88. doi: 10.1186/s12906-023-04333-w. BMC Complement Med Ther. 2024. PMID: 38355510 Free PMC article.
Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells.
Mersal KI, Abdel-Maksoud MS, Ali EMH, Ammar UM, Zaraei SO, Haque MM, Das T, Hassan NF, Kim EE, Lee JS, Park H, Lee KH, El-Gamal MI, Kim HK, Ibrahim TM, Oh CH. Mersal KI, et al. Among authors: hassan nf. Eur J Med Chem. 2023 Dec 5;261:115779. doi: 10.1016/j.ejmech.2023.115779. Epub 2023 Sep 15. Eur J Med Chem. 2023. PMID: 37776574
62 results