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Cilostazol counteracts mitochondrial dysfunction in hepatic encephalopathy rat model: Insights into the role of cAMP/AMPK/SIRT1/ PINK-1/parkin hub and p-CREB /BDNF/ TrkB neuroprotective trajectory.
Gad ES, Aldossary SA, El-Ansary MR, Abd El-Galil MM, Abd-El-Hamid AH, El-Ansary AR, Hassan NF. Gad ES, et al. Among authors: abd el galil mm. Eur J Pharmacol. 2024 Dec 10;987:177194. doi: 10.1016/j.ejphar.2024.177194. Online ahead of print. Eur J Pharmacol. 2024. PMID: 39667427
The potential role of Tirzepatide as adjuvant therapy in countering colistin-induced nephro and neurotoxicity in rats via modulation of PI3K/p-Akt/GSK3-β/NF-kB p65 hub, shielding against oxidative and endoplasmic reticulum stress, and activation of p-CREB/BDNF/TrkB cascade.
Hassan NF, Ragab D, Ibrahim SG, Abd El-Galil MM, Hassan Abd-El-Hamid A, Hamed DM, Magdy William M, Salem MA. Hassan NF, et al. Among authors: abd el galil mm. Int Immunopharmacol. 2024 Jun 30;135:112308. doi: 10.1016/j.intimp.2024.112308. Epub 2024 May 23. Int Immunopharmacol. 2024. PMID: 38788447
Apilarnil exerts neuroprotective effects and alleviates motor dysfunction by rebalancing M1/M2 microglia polarization, regulating miR-155 and miR-124 expression in a rotenone-induced Parkinson's disease rat model.
Salama RM, Darwish SF, Yehia R, Eissa N, Elmongy NF, Abd-Elgalil MM, Schaalan MF, El Wakeel SA. Salama RM, et al. Int Immunopharmacol. 2024 Aug 20;137:112536. doi: 10.1016/j.intimp.2024.112536. Epub 2024 Jun 22. Int Immunopharmacol. 2024. PMID: 38909495