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Page 1
Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia.
Swingle KL, Hamilton AG, Safford HC, Geisler HC, Thatte AS, Palanki R, Murray AM, Han EL, Mukalel AJ, Han X, Joseph RA, Ghalsasi AA, Alameh MG, Weissman D, Mitchell MJ. Swingle KL, et al. Among authors: thatte as. Nature. 2025 Jan;637(8045):412-421. doi: 10.1038/s41586-024-08291-2. Epub 2024 Dec 11. Nature. 2025. PMID: 39663452
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy.
Swingle KL, Safford HC, Geisler HC, Hamilton AG, Thatte AS, Billingsley MM, Joseph RA, Mrksich K, Padilla MS, Ghalsasi AA, Alameh MG, Weissman D, Mitchell MJ. Swingle KL, et al. Among authors: thatte as. J Am Chem Soc. 2023 Mar 1;145(8):4691-4706. doi: 10.1021/jacs.2c12893. Epub 2023 Feb 15. J Am Chem Soc. 2023. PMID: 36789893 Free PMC article.
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery.
Patel SK, Billingsley MM, Mukalel AJ, Thatte AS, Hamilton AG, Gong N, El-Mayta R, Safford HC, Merolle M, Mitchell MJ. Patel SK, et al. Among authors: thatte as. Theranostics. 2024 Jan 1;14(1):1-16. doi: 10.7150/thno.89913. eCollection 2024. Theranostics. 2024. PMID: 38164140 Free PMC article.
Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy.
Metzloff AE, Padilla MS, Gong N, Billingsley MM, Han X, Merolle M, Mai D, Figueroa-Espada CG, Thatte AS, Haley RM, Mukalel AJ, Hamilton AG, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ. Metzloff AE, et al. Among authors: thatte as. Adv Mater. 2024 Jun;36(26):e2313226. doi: 10.1002/adma.202313226. Epub 2024 Mar 15. Adv Mater. 2024. PMID: 38419362
In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells.
Palanki R, Riley JS, Bose SK, Luks V, Dave A, Kus N, White BM, Ricciardi AS, Swingle KL, Xue L, Sung D, Thatte AS, Safford HC, Chaluvadi VS, Carpenter M, Han EL, Maganti R, Hamilton AG, Mrksich K, Billingsley MB, Zoltick PW, Alameh MG, Weissman D, Mitchell MJ, Peranteau WH. Palanki R, et al. Among authors: thatte as. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2400783121. doi: 10.1073/pnas.2400783121. Epub 2024 Jul 30. Proc Natl Acad Sci U S A. 2024. PMID: 39078677
19 results