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Microglia as hunters or gatherers of brain synapses.
Pereira-Iglesias M, Maldonado-Teixido J, Melero A, Piriz J, Galea E, Ransohoff RM, Sierra A. Pereira-Iglesias M, et al. Nat Neurosci. 2025 Jan;28(1):15-23. doi: 10.1038/s41593-024-01818-w. Epub 2024 Dec 11. Nat Neurosci. 2025. PMID: 39663381 Review.
Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy.
Beccari S, Sierra-Torre V, Valero J, Pereira-Iglesias M, García-Zaballa M, Soria FN, De Las Heras-Garcia L, Carretero-Guillen A, Capetillo-Zarate E, Domercq M, Huguet PR, Ramonet D, Osman A, Han W, Dominguez C, Faust TE, Touzani O, Pampliega O, Boya P, Schafer D, Mariño G, Canet-Soulas E, Blomgren K, Plaza-Zabala A, Sierra A. Beccari S, et al. Among authors: pereira iglesias m. Autophagy. 2023 Jul;19(7):1952-1981. doi: 10.1080/15548627.2023.2165313. Epub 2023 Jan 20. Autophagy. 2023. PMID: 36622892 Free PMC article.
Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus.
Matera A, Compagnion AC, Pedicone C, Kotah JM, Ivanov A, Monsorno K, Labouèbe G, Leggio L, Pereira-Iglesias M, Beule D, Mansuy-Aubert V, Williams TL, Iraci N, Sierra A, Marro SG, Goate AM, Eggen BJL, Kerr WG, Paolicelli RC. Matera A, et al. Among authors: pereira iglesias m. Immunity. 2025 Jan 14;58(1):197-217.e13. doi: 10.1016/j.immuni.2024.11.003. Epub 2024 Dec 9. Immunity. 2025. PMID: 39657671 Free article.