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Page 1
ATP citrate lyase drives vascular remodeling in systemic and pulmonary vascular diseases through metabolic and epigenetic changes.
Grobs Y, Romanet C, Lemay SE, Bourgeois A, Voisine P, Theberge C, Sauvaget M, Breuils-Bonnet S, Martineau S, El Kabbout R, Valasarajan C, Chelladurai P, Pelletier A, Mougin M, Dumais E, Perron J, Flamand N, Potus F, Provencher S, Pullamsetti SS, Boucherat O, Bonnet S. Grobs Y, et al. Among authors: flamand n. Sci Transl Med. 2024 Dec 11;16(777):eado7824. doi: 10.1126/scitranslmed.ado7824. Epub 2024 Dec 11. Sci Transl Med. 2024. PMID: 39661707
Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways.
Turcotte C, Dumais É, Archambault AS, Martin C, Blanchet MR, Bissonnette É, Boulet LP, Laviolette M, Di Marzo V, Flamand N. Turcotte C, et al. Among authors: flamand n. J Leukoc Biol. 2019 Dec;106(6):1337-1347. doi: 10.1002/JLB.3A0919-049RRR. Epub 2019 Sep 26. J Leukoc Biol. 2019. PMID: 31556464 Free article.
Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in the skin and saliva.
Tinto F, Archambault AS, Dumais É, Rakotoarivelo V, Kostrzewa M, Martin C, Plante PL, Desjardins Y, Simard M, Pouliot R, De Petrocellis L, Ligresti A, Di Marzo V, Flamand N. Tinto F, et al. Among authors: flamand n. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Aug;1866(8):158954. doi: 10.1016/j.bbalip.2021.158954. Epub 2021 Apr 27. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 33915294
Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils.
Archambault AS, Tinto F, Dumais É, Rakotoarivelo V, Kostrzewa M, Plante PL, Martin C, Simard M, Silvestri C, Pouliot R, Laviolette M, Boulet LP, Vitale RM, Ligresti A, Di Marzo V, Flamand N. Archambault AS, et al. Among authors: flamand n. Cells. 2021 Sep 5;10(9):2322. doi: 10.3390/cells10092322. Cells. 2021. PMID: 34571971 Free PMC article.
Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoyl-glycerol and its congeners in human myeloid leukocytes.
Turcotte C, Archambault AS, Dumais É, Martin C, Blanchet MR, Bissonnette E, Ohashi N, Yamamoto K, Itoh T, Laviolette M, Veilleux A, Boulet LP, Di Marzo V, Flamand N. Turcotte C, et al. Among authors: flamand n. FASEB J. 2020 Mar;34(3):4253-4265. doi: 10.1096/fj.201902916R. Epub 2020 Feb 3. FASEB J. 2020. PMID: 32012340
115 results