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Page 1
ATP citrate lyase drives vascular remodeling in systemic and pulmonary vascular diseases through metabolic and epigenetic changes.
Grobs Y, Romanet C, Lemay SE, Bourgeois A, Voisine P, Theberge C, Sauvaget M, Breuils-Bonnet S, Martineau S, El Kabbout R, Valasarajan C, Chelladurai P, Pelletier A, Mougin M, Dumais E, Perron J, Flamand N, Potus F, Provencher S, Pullamsetti SS, Boucherat O, Bonnet S. Grobs Y, et al. Among authors: chelladurai p. Sci Transl Med. 2024 Dec 11;16(777):eado7824. doi: 10.1126/scitranslmed.ado7824. Epub 2024 Dec 11. Sci Transl Med. 2024. PMID: 39661707
Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension.
Chelladurai P, Kuenne C, Bourgeois A, Günther S, Valasarajan C, Cherian AV, Rottier RJ, Romanet C, Weigert A, Boucherat O, Eichstaedt CA, Ruppert C, Guenther A, Braun T, Looso M, Savai R, Seeger W, Bauer UM, Bonnet S, Pullamsetti SS. Chelladurai P, et al. Sci Transl Med. 2022 Jun 8;14(648):eabe5407. doi: 10.1126/scitranslmed.abe5407. Epub 2022 Jun 8. Sci Transl Med. 2022. PMID: 35675437
GLI1+ Cells Contribute to Vascular Remodeling in Pulmonary Hypertension.
Chu X, Kheirollahi V, Lingampally A, Chelladurai P, Valasarajan C, Vazquez-Armendariz AI, Hadzic S, Khadim A, Pak O, Rivetti S, Wilhelm J, Bartkuhn M, Crnkovic S, Moiseenko A, Heiner M, Kraut S, Atefi LS, Koepke J, Valente G, Ruppert C, Braun T, Samakovlis C, Alexopoulos I, Looso M, Chao CM, Herold S, Seeger W, Kwapiszewska G, Huang X, Zhang JS, Pullamsetti SS, Weissmann N, Li X, El Agha E, Bellusci S. Chu X, et al. Among authors: chelladurai p. Circ Res. 2024 May 24;134(11):e133-e149. doi: 10.1161/CIRCRESAHA.123.323736. Epub 2024 Apr 19. Circ Res. 2024. PMID: 38639105 Free article.
Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension.
Khassafi F, Chelladurai P, Valasarajan C, Nayakanti SR, Martineau S, Sommer N, Yokokawa T, Boucherat O, Kamal A, Kiely DG, Swift AJ, Alabed S, Omura J, Breuils-Bonnet S, Kuenne C, Potus F, Günther S, Savai R, Seeger W, Looso M, Lawrie A, Zaugg JB, Tello K, Provencher S, Bonnet S, Pullamsetti SS. Khassafi F, et al. Among authors: chelladurai p. Nat Cardiovasc Res. 2023 Oct;2(10):917-936. doi: 10.1038/s44161-023-00338-3. Epub 2023 Sep 28. Nat Cardiovasc Res. 2023. PMID: 39196250 Free PMC article.
Cancer and pulmonary hypertension: Learning lessons and real-life interplay.
Pullamsetti SS, Nayakanti S, Chelladurai P, Mamazhakypov A, Mansouri S, Savai R, Seeger W. Pullamsetti SS, et al. Among authors: chelladurai p. Glob Cardiol Sci Pract. 2020 Apr 30;2020(1):e202010. doi: 10.21542/gcsp.2020.10. Glob Cardiol Sci Pract. 2020. PMID: 33150154 Free PMC article. Review.
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