Varshney U - Search Results

1

An unusual activity of mycobacterial MutT1 Nudix hydrolase domain as a protein phosphatase regulates nucleoside diphosphate kinase function.

Emam EAF, Roy K, Singh DP, Saini DK, Varshney U. Emam EAF, et al. Among authors: varshney u. J Bacteriol. 2024 Dec 11:e0031424. doi: 10.1128/jb.00314-24. Online ahead of print. J Bacteriol. 2024. PMID: 39660902 Free article.

2

Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli.

Kapoor I, Emam EAF, Shaw A, Varshney U. Kapoor I, et al. Among authors: varshney u. J Bacteriol. 2019 Dec 6;202(1):e00567-19. doi: 10.1128/JB.00567-19. Print 2019 Dec 6. J Bacteriol. 2019. PMID: 31591275 Free PMC article.

3

Role of the nucleotide excision repair pathway proteins (UvrB and UvrD2) in recycling UdgB, a base excision repair enzyme in Mycobacterium smegmatis.

Kapoor I, Shaw A, Naha A, Emam EAF, Varshney U. Kapoor I, et al. Among authors: varshney u. DNA Repair (Amst). 2022 May;113:103316. doi: 10.1016/j.dnarep.2022.103316. Epub 2022 Mar 4. DNA Repair (Amst). 2022. PMID: 35306347

4

Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.

Kesharwani S, Raj P, Paul A, Roy K, Bhanot A, Mehta A, Gopal A, Varshney U, Gopal B, Sundriyal S. Kesharwani S, et al. Among authors: varshney u. Eur J Med Chem. 2023 Oct 5;258:115604. doi: 10.1016/j.ejmech.2023.115604. Epub 2023 Jun 28. Eur J Med Chem. 2023. PMID: 37399710

5

Identification of a new and diverse set of Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) inhibitors using structure-based virtual screening: Experimental validation and molecular dynamics studies.

Raj P, Selvam K, Roy K, Mani Tripathi S, Kesharwani S, Gopal B, Varshney U, Sundriyal S. Raj P, et al. Among authors: varshney u. Bioorg Med Chem Lett. 2022 Nov 15;76:129008. doi: 10.1016/j.bmcl.2022.129008. Epub 2022 Sep 27. Bioorg Med Chem Lett. 2022. PMID: 36174837

6

Biochemical properties of MutT2 proteins from Mycobacterium tuberculosis and M. smegmatis and their contrasting antimutator roles in Escherichia coli.

Sang PB, Varshney U. Sang PB, et al. Among authors: varshney u. J Bacteriol. 2013 Apr;195(7):1552-60. doi: 10.1128/JB.02102-12. Epub 2013 Jan 25. J Bacteriol. 2013. PMID: 23354752 Free PMC article.

7

Species-Specific Interactions of Arr with RplK Mediate Stringent Response in Bacteria.

Agrawal P, Varada R, Sah S, Bhattacharyya S, Varshney U. Agrawal P, et al. Among authors: varshney u. J Bacteriol. 2018 Feb 23;200(6):e00722-17. doi: 10.1128/JB.00722-17. Print 2018 Mar 15. J Bacteriol. 2018. PMID: 29311276 Free PMC article.

8

Contributions of the N- and C-Terminal Domains of Initiation Factor 3 to Its Functions in the Fidelity of Initiation and Antiassociation of the Ribosomal Subunits.

Ayyub SA, Dobriyal D, Varshney U. Ayyub SA, et al. Among authors: varshney u. J Bacteriol. 2017 May 9;199(11):e00051-17. doi: 10.1128/JB.00051-17. Print 2017 Jun 1. J Bacteriol. 2017. PMID: 28320882 Free PMC article.

9

Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association.

Arif SM, Patil AG, Varshney U, Vijayan M. Arif SM, et al. Among authors: varshney u. Acta Crystallogr D Struct Biol. 2017 Apr 1;73(Pt 4):349-364. doi: 10.1107/S2059798317002534. Epub 2017 Mar 31. Acta Crystallogr D Struct Biol. 2017. PMID: 28375146

10

Development of Assay Systems for Amber Codon Decoding at the Steps of Initiation and Elongation in Mycobacteria.

Govindan A, Miryala S, Mondal S, Varshney U. Govindan A, et al. Among authors: varshney u. J Bacteriol. 2018 Oct 23;200(22):e00372-18. doi: 10.1128/JB.00372-18. Print 2018 Nov 15. J Bacteriol. 2018. PMID: 30181124 Free PMC article.

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