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Warehouse-based, immunopeptidome-guided design of personalised peptide vaccines shows feasibility in clinical trial evaluation in CLL patients.
Heitmann JS, Jung S, Wacker M, Maringer Y, Nelde A, Bauer J, Denk M, Hoenisch-Gravel N, Richter M, Oezbek MT, Dubbelaar ML, Bilich T, Pumptow M, Martus P, Illerhaus G, Denzlinger C, Steinbach F, Aulitzky WE, Müller MR, Dörfel D, Rammensee HG, Salih HR, Walz JS. Heitmann JS, et al. Among authors: richter m. Front Immunol. 2024 Nov 26;15:1482715. doi: 10.3389/fimmu.2024.1482715. eCollection 2024. Front Immunol. 2024. PMID: 39660140 Free PMC article. Clinical Trial.
A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity.
Heitmann JS, Bilich T, Tandler C, Nelde A, Maringer Y, Marconato M, Reusch J, Jäger S, Denk M, Richter M, Anton L, Weber LM, Roerden M, Bauer J, Rieth J, Wacker M, Hörber S, Peter A, Meisner C, Fischer I, Löffler MW, Karbach J, Jäger E, Klein R, Rammensee HG, Salih HR, Walz JS. Heitmann JS, et al. Among authors: richter m. Nature. 2022 Jan;601(7894):617-622. doi: 10.1038/s41586-021-04232-5. Epub 2021 Nov 23. Nature. 2022. PMID: 34814158 Free PMC article. Clinical Trial.
The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma.
Bauer J, Köhler N, Maringer Y, Bucher P, Bilich T, Zwick M, Dicks S, Nelde A, Dubbelaar M, Scheid J, Wacker M, Heitmann JS, Schroeder S, Rieth J, Denk M, Richter M, Klein R, Bonzheim I, Luibrand J, Holzer U, Ebinger M, Brecht IB, Bitzer M, Boerries M, Feucht J, Salih HR, Rammensee HG, Hailfinger S, Walz JS. Bauer J, et al. Among authors: richter m. Nat Commun. 2022 Oct 27;13(1):6401. doi: 10.1038/s41467-022-33746-3. Nat Commun. 2022. PMID: 36302754 Free PMC article.
Phase I/II trial of a peptide-based COVID-19 T-cell activator in patients with B-cell deficiency.
Heitmann JS, Tandler C, Marconato M, Nelde A, Habibzada T, Rittig SM, Tegeler CM, Maringer Y, Jaeger SU, Denk M, Richter M, Oezbek MT, Wiesmüller KH, Bauer J, Rieth J, Wacker M, Schroeder SM, Hoenisch Gravel N, Scheid J, Märklin M, Henrich A, Klimovich B, Clar KL, Lutz M, Holzmayer S, Hörber S, Peter A, Meisner C, Fischer I, Löffler MW, Peuker CA, Habringer S, Goetze TO, Jäger E, Rammensee HG, Salih HR, Walz JS. Heitmann JS, et al. Among authors: richter m. Nat Commun. 2023 Aug 18;14(1):5032. doi: 10.1038/s41467-023-40758-0. Nat Commun. 2023. PMID: 37596280 Free PMC article. Clinical Trial.
Long-term efficacy of the peptide-based COVID-19 T cell activator CoVac-1 in healthy adults.
Tandler C, Heitmann JS, Michel TM, Marconato M, Jaeger SU, Tegeler CM, Denk M, Richter M, Oezbek MT, Maringer Y, Schroeder SM, Schneiderhan-Marra N, Wiesmüller KH, Bitzer M, Ruetalo N, Schindler M, Meisner C, Fischer I, Rammensee HG, Salih HR, Walz JS. Tandler C, et al. Among authors: richter m. Int J Infect Dis. 2024 Feb;139:69-77. doi: 10.1016/j.ijid.2023.11.009. Epub 2023 Nov 26. Int J Infect Dis. 2024. PMID: 38016500 Free article.
msiFlow: automated workflows for reproducible and scalable multimodal mass spectrometry imaging and microscopy data analysis.
Spangenberg P, Bessler S, Widera L, Bottek J, Richter M, Thiebes S, Siemes D, Krauß SD, Migas LG, Kasarla SS, Phapale P, Kleesiek J, Führer D, Moeller LC, Heuer H, Van de Plas R, Gunzer M, Soehnlein O, Soltwisch J, Shevchuk O, Dreisewerd K, Engel DR. Spangenberg P, et al. Among authors: richter m. Nat Commun. 2025 Jan 27;16(1):1065. doi: 10.1038/s41467-024-55306-7. Nat Commun. 2025. PMID: 39870624
The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes.
Eibach Y, Kreher S, Poetsch MS, Kho AL, Gaertner U, Clemen CS, Schröder R, Guo K, Milting H, Meder B, Potente M, Richter M, Schneider A, Meiners S, Gaute M, Braun T. Eibach Y, et al. Among authors: richter m. Sci Adv. 2025 Jan 24;11(4):eado3852. doi: 10.1126/sciadv.ado3852. Epub 2025 Jan 22. Sci Adv. 2025. PMID: 39841822 Free PMC article.
Molecular detection and typing of pathogenic Leptospira species from livestock and small mammals in Uganda.
Alinaitwe L, Wainaina MK, Dürr S, Kankya C, Kivali V, Bugeza J, Aturinda CJ, Lubega A, Mayer-Scholl A, Hoona JJ, Bahn P, Hammerl JA, Roesel K, Cook EAJ, Richter MH. Alinaitwe L, et al. Among authors: richter mh. Epidemiol Infect. 2025 Jan 22:1-24. doi: 10.1017/S0950268825000044. Online ahead of print. Epidemiol Infect. 2025. PMID: 39838921 No abstract available.
2,801 results