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Warehouse-based, immunopeptidome-guided design of personalised peptide vaccines shows feasibility in clinical trial evaluation in CLL patients.
Heitmann JS, Jung S, Wacker M, Maringer Y, Nelde A, Bauer J, Denk M, Hoenisch-Gravel N, Richter M, Oezbek MT, Dubbelaar ML, Bilich T, Pumptow M, Martus P, Illerhaus G, Denzlinger C, Steinbach F, Aulitzky WE, Müller MR, Dörfel D, Rammensee HG, Salih HR, Walz JS. Heitmann JS, et al. Among authors: muller mr. Front Immunol. 2024 Nov 26;15:1482715. doi: 10.3389/fimmu.2024.1482715. eCollection 2024. Front Immunol. 2024. PMID: 39660140 Free PMC article. Clinical Trial.
Genetic Loss of LCK Kinase Leads to Acceleration of Chronic Lymphocytic Leukemia.
Märklin M, Fuchs AR, Tandler C, Heitmann JS, Salih HR, Kauer J, Quintanilla-Martinez L, Wirths S, Kopp HG, Müller MR. Märklin M, et al. Among authors: muller mr. Front Immunol. 2020 Sep 2;11:1995. doi: 10.3389/fimmu.2020.01995. eCollection 2020. Front Immunol. 2020. PMID: 32983140 Free PMC article.
NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.
Märklin M, Heitmann JS, Fuchs AR, Truckenmüller FM, Gutknecht M, Bugl S, Saur SJ, Lazarus J, Kohlhofer U, Quintanilla-Martinez L, Rammensee HG, Salih HR, Kopp HG, Haap M, Kirschniak A, Kanz L, Rao A, Wirths S, Müller MR. Märklin M, et al. Among authors: muller mr. Nat Commun. 2017 Oct 2;8(1):755. doi: 10.1038/s41467-017-00830-y. Nat Commun. 2017. PMID: 28970470 Free PMC article.
Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients.
Rittig SM, Haentschel M, Weimer KJ, Heine A, Muller MR, Brugger W, Horger MS, Maksimovic O, Stenzl A, Hoerr I, Rammensee HG, Holderried TA, Kanz L, Pascolo S, Brossart P. Rittig SM, et al. Among authors: muller mr. Mol Ther. 2011 May;19(5):990-9. doi: 10.1038/mt.2010.289. Epub 2010 Dec 28. Mol Ther. 2011. PMID: 21189474 Free PMC article. Clinical Trial.
The BCR-ABL inhibitor nilotinib influences phenotype and function of monocyte-derived human dendritic cells.
Dörfel D, Lechner CJ, Joas S, Funk T, Gutknecht M, Salih J, Geiger J, Kropp KN, Maurer S, Müller MR, Kopp HG, Salih HR, Grünebach F, Rittig SM. Dörfel D, et al. Among authors: muller mr. Cancer Immunol Immunother. 2018 May;67(5):775-783. doi: 10.1007/s00262-018-2129-9. Epub 2018 Feb 21. Cancer Immunol Immunother. 2018. PMID: 29468363 Free PMC article.
198 results