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Warehouse-based, immunopeptidome-guided design of personalised peptide vaccines shows feasibility in clinical trial evaluation in CLL patients.
Front Immunol. 2024 Nov 26;15:1482715. doi: 10.3389/fimmu.2024.1482715. eCollection 2024.
Front Immunol. 2024.
PMID: 39660140
Free PMC article.
Clinical Trial.
TOFIMS mass spectrometry-based immunopeptidomics refines tumor antigen identification.
Hoenisch Gravel N, Nelde A, Bauer J, Mühlenbruch L, Schroeder SM, Neidert MC, Scheid J, Lemke S, Dubbelaar ML, Wacker M, Dengler A, Klein R, Mauz PS, Löwenheim H, Hauri-Hohl M, Martin R, Hennenlotter J, Stenzl A, Heitmann JS, Salih HR, Rammensee HG, Walz JS.
Hoenisch Gravel N, et al.
Nat Commun. 2023 Nov 17;14(1):7472. doi: 10.1038/s41467-023-42692-7.
Nat Commun. 2023.
PMID: 37978195
Free PMC article.
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Phase I/II trial of a peptide-based COVID-19 T-cell activator in patients with B-cell deficiency.
Heitmann JS, Tandler C, Marconato M, Nelde A, Habibzada T, Rittig SM, Tegeler CM, Maringer Y, Jaeger SU, Denk M, Richter M, Oezbek MT, Wiesmüller KH, Bauer J, Rieth J, Wacker M, Schroeder SM, Hoenisch Gravel N, Scheid J, Märklin M, Henrich A, Klimovich B, Clar KL, Lutz M, Holzmayer S, Hörber S, Peter A, Meisner C, Fischer I, Löffler MW, Peuker CA, Habringer S, Goetze TO, Jäger E, Rammensee HG, Salih HR, Walz JS.
Heitmann JS, et al. Among authors: hoenisch gravel n.
Nat Commun. 2023 Aug 18;14(1):5032. doi: 10.1038/s41467-023-40758-0.
Nat Commun. 2023.
PMID: 37596280
Free PMC article.
Clinical Trial.
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Increased soluble HLA in COVID-19 present a disease-related, diverse immunopeptidome associated with T cell immunity.
Nelde A, Rieth J, Roerden M, Dubbelaar ML, Hoenisch Gravel N, Bauer J, Klein R, Hoheisel T, Mahrhofer H, Göpel S, Bitzer M, Hörber S, Peter A, Heitmann JS, Walz JS.
Nelde A, et al. Among authors: hoenisch gravel n.
iScience. 2022 Dec 22;25(12):105643. doi: 10.1016/j.isci.2022.105643. Epub 2022 Nov 19.
iScience. 2022.
PMID: 36439376
Free PMC article.
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