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Necrosome-positive granulovacuolar degeneration is associated with TDP-43 pathological lesions in the hippocampus of ALS/FTLD cases.
Van Schoor E, Koper MJ, Ospitalieri S, Dedeene L, Tomé SO, Vandenberghe R, Brenner D, Otto M, Weishaupt J, Ludolph AC, Van Damme P, Van Den Bosch L, Thal DR. Van Schoor E, et al. Among authors: tome so. Neuropathol Appl Neurobiol. 2021 Feb;47(2):328-345. doi: 10.1111/nan.12668. Epub 2020 Oct 20. Neuropathol Appl Neurobiol. 2021. PMID: 32949047
Maturation of neuronal AD-tau pathology involves site-specific phosphorylation of cytoplasmic and synaptic tau preceding conformational change and fibril formation.
Aragão Gomes L, Uytterhoeven V, Lopez-Sanmartin D, Tomé SO, Tousseyn T, Vandenberghe R, Vandenbulcke M, von Arnim CAF, Verstreken P, Thal DR. Aragão Gomes L, et al. Among authors: tome so. Acta Neuropathol. 2021 Feb;141(2):173-192. doi: 10.1007/s00401-020-02251-6. Epub 2021 Jan 11. Acta Neuropathol. 2021. PMID: 33427938
LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease.
Koper MJ, Tomé SO, Gawor K, Belet A, Van Schoor E, Schaeverbeke J, Vandenberghe R, Vandenbulcke M, Ghebremedhin E, Otto M, von Arnim CAF, Balusu S, Blaschko MB, De Strooper B, Thal DR. Koper MJ, et al. Among authors: tome so. Acta Neuropathol Commun. 2022 Sep 3;10(1):128. doi: 10.1186/s40478-022-01432-6. Acta Neuropathol Commun. 2022. PMID: 36057624 Free PMC article.
17 results