Watson MA - Search Results

1

Exogenous expression of ATP8, a mitochondrial encoded protein, from the nucleus in vivo.

Begelman DV, Dixit B, Truong C, King CD, Watson MA, Schilling B, Brand MD, Boominathan A. Begelman DV, et al. Among authors: watson ma. Mol Ther Methods Clin Dev. 2024 Nov 6;32(4):101372. doi: 10.1016/j.omtm.2024.101372. eCollection 2024 Dec 12. Mol Ther Methods Clin Dev. 2024. PMID: 39659757 Free PMC article.

2

Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes.

Watson MA, Wong HS, Brand MD. Watson MA, et al. Biochem Soc Trans. 2019 Oct 31;47(5):1461-1469. doi: 10.1042/BST20190305. Biochem Soc Trans. 2019. PMID: 31506330 Review.

3

Controlled power: how biology manages succinate-driven energy release.

Mookerjee SA, Gerencser AA, Watson MA, Brand MD. Mookerjee SA, et al. Among authors: watson ma. Biochem Soc Trans. 2021 Dec 17;49(6):2929-2939. doi: 10.1042/BST20211032. Biochem Soc Trans. 2021. PMID: 34882231 Free PMC article.

4

The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production.

Goncalves RLS, Watson MA, Wong HS, Orr AL, Brand MD. Goncalves RLS, et al. Among authors: watson ma. Redox Biol. 2020 Jan;28:101341. doi: 10.1016/j.redox.2019.101341. Epub 2019 Oct 9. Redox Biol. 2020. PMID: 31627168 Free PMC article.

5

Site IQ in mitochondrial complex I generates S1QEL-sensitive superoxide/hydrogen peroxide in both the reverse and forward reactions.

Gibbs ET, Lerner CA, Watson MA, Wong HS, Gerencser AA, Brand MD. Gibbs ET, et al. Among authors: watson ma. Biochem J. 2023 Mar 15;480(5):363-384. doi: 10.1042/BCJ20220611. Biochem J. 2023. PMID: 36862427 Free PMC article.

6

S3QELs protect against diet-induced intestinal barrier dysfunction.

Watson MA, Pattavina B, Hilsabeck TAU, Lopez-Dominguez J, Kapahi P, Brand MD. Watson MA, et al. Aging Cell. 2021 Oct;20(10):e13476. doi: 10.1111/acel.13476. Epub 2021 Sep 14. Aging Cell. 2021. PMID: 34521156 Free PMC article.

7

Suppression of superoxide/hydrogen peroxide production at mitochondrial site I_Q decreases fat accumulation, improves glucose tolerance and normalizes fasting insulin concentration in mice fed a high-fat diet.

Watson MA, Brar H, Gibbs ET 2nd, Wong HS, Dighe PA, McKibben B, Riedmaier S, Siu A, Polakowski JS, Segreti JA, Liu X, Chung S, Pliushchev YM, Gesmundo N, Wang Z, Vortherms TA, Brand MD. Watson MA, et al. Free Radic Biol Med. 2023 Aug 1;204:276-286. doi: 10.1016/j.freeradbiomed.2023.05.022. Epub 2023 May 20. Free Radic Biol Med. 2023. PMID: 37217089 Free article.

8

Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila.

Sharma A, Akagi K, Pattavina B, Wilson KA, Nelson C, Watson M, Maksoud E, Harata A, Ortega M, Brem RB, Kapahi P. Sharma A, et al. Sci Rep. 2020 Nov 5;10(1):19080. doi: 10.1038/s41598-020-75867-z. Sci Rep. 2020. PMID: 33154387 Free PMC article.

9

A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster.

Lang S, Hilsabeck TA, Wilson KA, Sharma A, Bose N, Brackman DJ, Beck JN, Chen L, Watson MA, Killilea DW, Ho S, Kahn A, Giacomini K, Stoller ML, Chi T, Kapahi P. Lang S, et al. Among authors: watson ma. PLoS Genet. 2019 Aug 15;15(8):e1008318. doi: 10.1371/journal.pgen.1008318. eCollection 2019 Aug. PLoS Genet. 2019. PMID: 31415568 Free PMC article.

10

Active Monitoring With or Without Endocrine Therapy for Low-Risk Ductal Carcinoma In Situ: The COMET Randomized Clinical Trial.

Hwang ES, Hyslop T, Lynch T, Ryser MD, Weiss A, Wolf A, Norris K, Witten M, Grimm L, Schnitt S, Badve S, Factor R, Frank E, Collyar D, Basila D, Pinto D, Watson MA, West R, Davies L, Donovan JL, Shimada A, Li Y, Li Y, Bennett AV, Rosenberg S, Marks J, Winer E, Boisvert M, Giuliano A, Larson KE, Yost K, McAuliffe PF, Krie A, Tamirisa N, Carey LA, Thompson AM, Partridge AH; COMET Study Investigators. Hwang ES, et al. Among authors: watson ma. JAMA. 2024 Dec 12. doi: 10.1001/jama.2024.26698. Online ahead of print. JAMA. 2024. PMID: 39665585

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